Insights into human norovirus cultivation in human intestinal enteroids
mSphereABSTRACT Human noroviruses (HuNoVs) are a significant cause of epidemic and sporadic acute gastroenteritis worldwide. The lack of a reproducible culture system hindered the study of HuNoV replication and pathogenesis for almost a half-century.
Khalil Ettayebi +15 more
openaire +4 more sources
A Dynamic Quantitative Microbial Risk Assessment for Norovirus in Potable Reuse System [PDF]
, 2019 This study describes the results of a dynamic quantitative microbial risk assessment (QMRA) for norovirus (NoV) that was used to evaluate the relative significance of foodborne, person-to-person, and person-to-sewage-to-person transmission pathways. This
Ahmad, Sajjad +3 more
core +1 more source
Strategies to reduce microbial risk and improve quality of fresh and processed strawberries: A review [PDF]
, 2019 Strawberries are one of the most important fruits in the Mediterranean diet and have been widely investigatedfor their nutritional and nutraceutical properties. Concern about the safety of fresh and processed strawberrieshas increased in recent years due
Abadias i Sero, Mª Isabel +5 more
core +3 more sources
Journal of Fish Diseases, EarlyView.ABSTRACT Salovirus is a genus within the family Caliciviridae, which contains a single member species, Salovirus nordlandense, also known as Atlantic salmon calicivirus (ASCV). While previous work has shown that ASCV can replicate in fish cell lines and establish systemic infection in vivo, its exact role in disease remains unclear and very little is ...
Vincenzo A. Costa +2 more
wiley +1 more source
Lack of Effect of Murine Norovirus Infection on a Mouse Model of Bacteria-Induced Colon Cancer [PDF]
, 2011 Murine norovirus (MNV) is endemic in mouse research facilities in the United States and Europe, with a prevalence as high as 58% to 64%. Because of MNV's orofecal route of infection, clinically silent persistent infections in some mouse strains, and ...
Brabb, Thea +5 more
core +1 more source
Use of Human Intestinal Enteroids to Detect Human Norovirus Infectivity
Emerging Infectious Diseases, 2019 Tools to detect human norovirus infectivity have been lacking. Using human intestinal enteroid cultures inoculated with GII.Pe-GII.4 Sydney–infected fecal samples, we determined that a real-time reverse transcription PCR cycle threshold cutoff of 30 may ...
Martin Chi-Wai Chan +5 more
doaj +1 more source
Diagnostic electron microscopy in human infectious diseases – Methods and applications
Journal of Microscopy, EarlyView.Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley +1 more source
Identification of immune and viral correlates of norovirus protective immunity through comparative study of intra-cluster norovirus strains. [PDF]
PLoS Pathogens, 2013 Whether or not primary norovirus infections induce protective immunity has become a controversial issue, potentially confounded by the comparison of data from genetically distinct norovirus strains.
Shu Zhu +12 more
doaj +1 more source
Periodically stationary multivariate autoregressive models [PDF]
arXiv, 2017 A class of multivariate periodic autoregressive models is proposed where coupling between time series is achieved through linear mean functions. Various response distributions with quadratic mean-variance relationships fit into the framework, including the negative binomial, gamma and Gaussian distributions.
arxiv
Human-robot co-manipulation of extended objects: Data-driven models and control from analysis of human-human dyads [PDF]
arXiv, 2020 Human teams are able to easily perform collaborative manipulation tasks. However, for a robot and human to simultaneously manipulate an extended object is a difficult task using existing methods from the literature. Our approach in this paper is to use data from human-human dyad experiments to determine motion intent which we use for a physical human ...
arxiv