Results 21 to 30 of about 38,742 (265)

A Mouse Model for Human Norovirus [PDF]

mBio, 2013
ABSTRACT Human noroviruses (HuNoVs) cause significant morbidity and mortality worldwide. However, despite substantial efforts, a small-animal model for HuNoV has not been described to date. Since “humanized” mice have been successfully used to study human-tropic pathogens in the past, we challenged BALB/c mice deficient in ...
Taube, Stefan, Kolawole, Abimbola O, Hohne, Marina, Wilkinson, John E, Handley, Scott A, Perry, Jeffrey W, Thackray, Larissa B, Akkina, Ramesh, Wobus, Christiane E   +8 more
openaire   +5 more sources

Insights into human norovirus cultivation in human intestinal enteroids. [PDF]

mSphere
ABSTRACT Human noroviruses (HuNoVs) are a significant cause of epidemic and sporadic acute gastroenteritis worldwide. The lack of a reproducible culture system hindered the study of HuNoV replication and pathogenesis for almost a half-century.
Ettayebi K, Kaur G, Patil K, Dave J, Ayyar BV, Tenge VR, Neill FH, Zeng X-L, Speer AL, Di Rienzi SC, Britton RA, Blutt SE, Crawford SE, Ramani S, Atmar RL, Estes MK.   +15 more
europepmc   +6 more sources

Human norovirus infection in Latin America [PDF]

Journal of Clinical Virology, 2016
Noroviruses are important enteric pathogens involved in non-bacterial gastroenteritis outbreaks worldwide. Noroviruses mainly occur from person to person via the fecal-oral route but also through contaminated food or water; indirect contamination is also possible due to the resistance of the virus in the environment. Latin American countries as a whole
da Silva Polo, Tatiane, Peiro, Juliana, Claudio Nogueira Mendes, Luiz, Ludwig, Louisa, de Oliveira-Filho, Edmilson, Bucardo, Filemon, HUYNEN, Pascale, Melin, Pierrette, Thiry, Etienne, Mauroy, Axel   +9 more
openaire   +2 more sources

Clinical characteristics and risk factors for children with norovirus gastroenteritis in Taiwan

Journal of Microbiology, Immunology and Infection, 2021
Background: Norovirus is a common acute gastroenteritis (AGE) pathogen across all age groups worldwide, which is difficult to differentiate from other pathogens.
Chia-Yi Wu, Hsin Chi, Ching-Chuan Liu, Yhu-Chering Huang, Yi-Chuan Huang, Hsiao-Chuan Lin, Yu-Huai Ho, Li-Min Huang, Ching-Yi Huang, Shu-Man Shih, Fang-Tzy Wu, Jung-Jung Mu, Chao A. Hsiung   +12 more
doaj   +1 more source

In Vitro Replication of Human Norovirus [PDF]

Viruses, 2019
Human norovirus (HuNoV) infection is a major cause of gastroenteritis all over the world. Despite this, these non-enveloped RNA viruses are poorly characterized due to the lack of robust and widely available HuNoV culture systems. The two published systems (B cell line and stem cell-derived enteroids) support replication of HuNoVs but the levels of ...
Sutonuka Bhar, Melissa K. Jones
openaire   +3 more sources

Human norovirus culture in B cells [PDF]

Nature Protocols, 2015
Human noroviruses (HuNoVs) are a leading cause of foodborne disease and severe childhood diarrhea, and they cause a majority of the gastroenteritis outbreaks worldwide. However, the development of effective and long-lasting HuNoV vaccines and therapeutics has been greatly hindered by their uncultivability.
Jones, MK, Grau, KR, Costantini, V, Kolawole, AO, de Graaf, Miranda, Freiden, P, Graves, CL, Koopmans, Marion, Wallet, SM, Tibbetts, SA, Schultz-Cherry, S, Wobus, CE, Vinje, J, Karst, SM   +13 more
openaire   +2 more sources

Specific Interactions between Human Norovirus and Environmental Matrices: Effects on the Virus Ecology

Viruses, 2019
Human norovirus is the major cause of non-bacterial epidemic gastroenteritis. Human norovirus binds to environmental solids via specific and non-specific interactions, and several specific receptors for human norovirus have been reported.
Mohan Amarasiri, Daisuke Sano
doaj   +1 more source

Persistence of Infectious Human Norovirus in Estuarine Water. [PDF]

Food Environ Virol
Rexin D, Rachmadi AT, Hewitt J.
europepmc   +3 more sources

Human Norovirus prevalence in Africa:a review of studies from 1990 to 2013 [PDF]

, 2016
OBJECTIVES: To assess the contribution of Human Norovirus to diarrheal diseases in Africa.   METHODS: We conducted a systematic review of the PubMed and EMBASE databases for published articles of Human Norovirus in Africa between 1990 and 2013. Data were
Abugalia, Ahenda, Ahmed, Armah, Asten, Atmar, Atmar, Ayukekbong, Ayukekbong, Azenabor, Benabbes, Boschi-Pinto, Bucardo, Bull, CDC-Division of viral diseases, Cegielski, Centers for Disease Control and Prevention (CDC), Centers for Disease Control and Prevention (CDC), Charles, Daniels, Dove, Duizer, El-Mohammady, El-Senousy, Elamri, Ferreira, Gibson, Green, Green, Greenberg, Hall, Hanoman, Hassine-Zaafrane, Hoa Tran, Huynen, Iwai, Jiang, Kabayiza, Kamel, Kamel, Kapikian, Karst, Kiulia, Kotloff, Kremer, Krumkamp, Kukkula, Le Guyader, Lee, Lindesmith, Liu, Liu, Lopman, Lysén, Mans, Mans, Maslin, Matthews, Mattison, Maunula, Medici, Milbrath, Mitchell, Moyo, Moyo, Murray, Nakata, Nordgren, Nourlil, Oluwatoyin, Papaventsis, Patel, Patel, Pavone, Payne, Pickering, Polo, Pommier de Santi, Rahouma, Ramani, Reither, Reuter, Rockx, Rodriguez-Diaz, Schilling, Sdiri-Loulizi, Sdiri-Loulizi, Sdiri-Loulizi, Seitz, Shieh, Siebenga, Siebenga, Silva, Silverman, Smit, Smit, Taylor, Taylor, Taylor, Thea, Trainor, Trujillo, Uhnoo, Wolfaardt, Wolfaardt, Xi, Yassin, Zeng, Zheng   +108 more
core   +1 more source

Norovirus Binding to Ligands Beyond Histo-Blood Group Antigens

Frontiers in Microbiology, 2017
Histo-blood group antigens (HBGAs) are commonly accepted as the cellular receptors for human norovirus. However, some human noroviruses have been found not to bind any HBGA ligand, suggesting potential additional co-factors.
Erin A. Almand, Matthew D. Moore, Matthew D. Moore, Lee-Ann Jaykus   +3 more
doaj   +1 more source