Human Norovirus Replication in Human Intestinal Enteroids as Model to Evaluate Virus Inactivation
Emerging Infectious Diseases, 2018 Human noroviruses are a leading cause of epidemic and endemic acute gastroenteritis worldwide and a leading cause of foodborne illness in the United States.
Veronica Costantini +7 more
doaj +1 more source
Understanding the relationship between norovirus diversity and immunity
Gut Microbes, 2021 Human noroviruses are the most common viral cause of acute gastroenteritis worldwide. Currently, there are no approved vaccines or specific therapeutics to treat the disease.
Lauren A. Ford-Siltz +2 more
doaj +1 more source
Molecular Evolution of Human Norovirus GII.2 Clusters
Frontiers in Microbiology, 2021 BackgroundThe human norovirus GII.2 outbreak during the 2016–2017 winter season was of unprecedented scale and geographic distribution.MethodsWe analyzed 519 complete VP1 gene sequences of the human norovirus GII.2 genotype sampled during the 2016–2017 ...
Xingguang Li +4 more
doaj +1 more source
Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]
, 2013 Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E. +4 more
core +2 more sources
Application of Chitosan Microparticles against Human Norovirus
Journal of Food Protection, 2021 Human norovirus (HuNoV) is the leading cause of foodborne illness outbreaks and the second most common cause of waterborne infections in the United States. The goal of this research was to investigate the antiviral activity of chitosan microparticles (CMs) against HuNoV GII.4 Sydney and its cultivable surrogate Tulane virus (TuV) in suspensions ...
Candace Barnes +6 more
openaire +2 more sources
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection
Nature Communications, 2023 Culture methods for studying human norovirus infection have been recently established. Here, Ayyar and colleagues use human intestinal enteroids to dissect viral entry mechanisms and show that CLIC-mediated endocytosis and wound repair pathways are ...
B. Vijayalakshmi Ayyar +10 more
doaj +1 more source
Drivers of Microbial Risk for Direct Potable Reuse and de Facto Reuse Treatment Schemes: The Impacts of Source Water Quality and Blending. [PDF]
, 2017 Although reclaimed water for potable applications has many potential benefits, it poses concerns for chemical and microbial risks to consumers. We present a quantitative microbial risk assessment (QMRA) Monte Carlo framework to compare a de facto water ...
Chaudhry, Rabia M +3 more
core +2 more sources
Preventing Foodborne Illness: Norovirus
EDIS, 2015 If you have ever had the stomach flu, norovirus was likely the culprit. Norovirus is the most common cause of foodborne illness in the United States and is transmitted through direct person-to-person contact or contaminated objects and food.
Rachael Silverberg +4 more
doaj +5 more sources
Development of Antibody-Fragment–Producing Rice for Neutralization of Human Norovirus
Frontiers in Plant Science, 2021 Human norovirus is the leading cause of acute nonbacterial gastroenteritis in people of all ages worldwide. Currently, no licensed norovirus vaccine, pharmaceutical drug, or therapy is available for the control of norovirus infection.
Ai Sasou +23 more
doaj +1 more source
Mendelian resistance to human norovirus infections
Seminars in Immunology, 2006 Noroviruses have emerged as a major cause of acute gastroenteritis in humans of all ages. Despite high infectivity of the virus and lack of long-term immunity, volunteer and authentic studies has suggested the existence of inherited protective factors.
Le Pendu, Jacques +3 more
openaire +2 more sources