Understanding the relationship between norovirus diversity and immunity
Gut Microbes, 2021 Human noroviruses are the most common viral cause of acute gastroenteritis worldwide. Currently, there are no approved vaccines or specific therapeutics to treat the disease.
Lauren A. Ford-Siltz +2 more
doaj +1 more source
The contact network of patients in a regional healthcare system [PDF]
Mathematical Population Studies 14, (2007) 269-284, 2005 Yet in spite of advances in hospital treatment, hospitals continue to be a breeding ground for several airborne diseases and for diseases that are transmitted through close contacts like SARS, methicillin-resistant Staphylococcus aureus (MRSA), norovirus infections and tuberculosis (TB). Here we extract contact networks for up to 295,108 inpatients for
arxiv +1 more source
Unraveling the mechanisms involved in human norovirus pathogenesis: An update in norovirus pathogenesis [PDF]
Revista Medicina Universitaria, 2021 RNA viruses causing human diseases impinge public health and the worldwide economy, as are the case of the current SARS-CoV-2 pandemic. These infectious pathogens are well known to control cellular machinery to complete their replication cycle, specifically taking advantage of the endoplasmic reticulum membrane to build replication complexes (RCs ...
Magda E. Vera-Garcia +8 more
openaire +2 more sources
New proof-of-concept in viral inactivation: virucidal efficacy of 405 nm light against feline calicivirus as a model for norovirus decontamination [PDF]
, 2016 The requirement for novel decontamination technologies for use in hospitals is ever present. One such system uses 405 nm visible light to inactivate microorganisms via ROS-generated oxidative damage.
Anderson, John G. +7 more
core +1 more source
Preventing Foodborne Illness: Norovirus
EDIS, 2015 If you have ever had the stomach flu, norovirus was likely the culprit. Norovirus is the most common cause of foodborne illness in the United States and is transmitted through direct person-to-person contact or contaminated objects and food.
Rachael Silverberg +4 more
doaj +5 more sources
Human Norovirus Replication in Human Intestinal Enteroids as Model to Evaluate Virus Inactivation
Emerging Infectious Diseases, 2018 Human noroviruses are a leading cause of epidemic and endemic acute gastroenteritis worldwide and a leading cause of foodborne illness in the United States.
Veronica Costantini +7 more
doaj +1 more source
Forecasting Based on Surveillance Data [PDF]
Handbook of Infectious Disease Data Analysis; Chapman & Hall/CRC,
2019; Chapter 25, 2018 Forecasting the future course of epidemics has always been one of the main goals of epidemic modelling. This chapter reviews statistical methods to quantify the accuracy of epidemic forecasts. We distinguish point and probabilistic forecasts and describe different methods to evaluate and compare the predictive performance across models.
arxiv +1 more source
Dasabuvir inhibits human norovirus infection in human intestinal enteroids [PDF]
mSphere, 2021 AbstractHuman noroviruses (HuNoVs) are acute viral gastroenteritis pathogens that affect all age groups, yet no approved vaccines and drugs to treat HuNoV infection are available. In this study, with a human intestinal enteroid (HIE) culture system where HuNoVs are able to replicate reproducibly, we screened an antiviral compound library to identify ...
Yoshiki Fujii +10 more
openaire +5 more sources
Norovirus Infection and Disease in an Ecuadorian Birth Cohort: Association of Certain Norovirus Genotypes With Host FUT2 Secretor Status. [PDF]
, 2015 BACKGROUND: Although norovirus is the most common cause of gastroenteritis, there are few data on the community incidence of infection/disease or the patterns of acquired immunity or innate resistance to norovirus.
Broncano, N +12 more
core +1 more source
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection
Nature Communications, 2023 Culture methods for studying human norovirus infection have been recently established. Here, Ayyar and colleagues use human intestinal enteroids to dissect viral entry mechanisms and show that CLIC-mediated endocytosis and wound repair pathways are ...
B. Vijayalakshmi Ayyar +10 more
doaj +1 more source