Results 151 to 160 of about 72,605 (256)

Combining radiotherapy with CAR‐T cell therapy for solid tumors: Challenges, mechanisms, and future directions

Precision Radiation Oncology, EarlyView.
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu, Xingyu Zhou, Jiao Xue, Xiaokang Zhang, Songbing Qin   +4 more
wiley   +1 more source

Skeletal muscle status and malnutrition as predictors of short‐term radiotherapy response and oral mucositis in head and neck cancer

Precision Radiation Oncology, EarlyView.
Baseline muscle mass and malnutrition were not decisive for short‐term radiotherapy outcomes in advanced head‐and‐neck cancer, yet diminished hand‐grip strength signaled poorer tumor response. This suggests that functional muscle metrics may serve as an accessible, actionable biomarker warranting validation in larger longitudinal cohorts.
Haomiao Zhang, Xiaonan Hu, Junying Zhao, Mingxin Zhang, Yang You, Wencheng Shao, Lili Yu   +6 more
wiley   +1 more source

Facility Type Predicts Treatment Regimen for Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Treatment landscapes are changing for HPV+ oropharyngeal cancer (OPC) without compromising oncologic outcomes. We aim to analyze treatment trends of HPV+ OPC at academic (ACs) and nonacademic centers (NACs). Methods The National Cancer Database was queried, and multinomial logistic regression was used to predict treatment trends ...
Monica S. Trent, Kelsey Roman, Timothy I. Hsu, Yarah M. Haidar, Tjoson Tjoa   +4 more
wiley   +1 more source

Comparison of Cervical Screening at 6‐ and 12‐Weeks Postnatal: A Paired‐Sample Feasibility Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Feasibility of a paired‐sample study comparing cervical screening and urine self‐sampling at 6‐ and 12‐weeks postnatal. Design Paired‐sample feasibility study. Setting Acute hospital. Population or Sample Females within 6 weeks of childbirth. Methods Paired‐sample study comparing cervical screening and high‐risk human papillomavirus (
Victoria A. Cullimore, Tessa Dean, Kim Chu, Adam Brentnall, Karin Denton, Katherine Hunt, Alexandra Sargent, Laura Johns, Katharine Edey, Sarah L. Coleridge, Jane Borley, Rebecca Newhouse, Holly Baker‐Rand, Lorna McWilliams, Emma J. Davidson, Jo Morrison   +15 more
wiley   +1 more source

Voice of Asia: Provision of Patient‐Centered Care in Oral Cavity Cancer: A Qualitative Study With Patients, Caregivers, and Healthcare Professionals in Five Asia‐Pacific Regions

Asia-Pacific Journal of Clinical Oncology, EarlyView.
The study identified key barriers to optimal patient‐centered care, including delayed diagnosis due to awareness and stigma‐related barriers among patients and caregivers, and opportunities to enhance multidisciplinary coordination. Resource limitations impacted nursing and psychosocial support, while access to support care varied across regions.
Edwin Pun Hui, Puma Sundaresan, Hye Ryun Kim, Khoi Tuan Nguyen, Tracey E Nicholls, Hai‐Ling Teng, Yu‐Chung Li, Ying Jie Yew, Regina Gowindah, Con Stylianou, Pei‐Jen Lou   +10 more
wiley   +1 more source

Real‐world evaluation of a population‐based vaginal self‐sampling program for cervical cancer prevention in Region Skåne, Sweden

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Large‐scale HPV self‐sampling screening distributed 557 976 kits, resulting in 208 386 returned samples with 98% validity. HPV positivity was detected in 19% of participants, leading to clinical follow‐up. Biopsy confirmed 980 high‐grade cervical lesions and 32 cervical cancers.
Caroline Hellsten, Ola Forslund, Christer Borgfeldt   +2 more
wiley   +1 more source

Rationale for Recommending Varicella Vaccination Into the Swedish National Immunisation Programme

Acta Paediatrica, EarlyView.
ABSTRACT Aim Under Swedish law, a vaccination may be included in the National Immunisation Programme (NIP) if it effectively prevents transmission in the population, is cost‐effective and aligns with ethical and humanitarian principles. The Public Health Agency of Sweden (PHAS) evaluated these criteria for introducing varicella vaccination. Methods The
Annika Ersson, Kari Johansen, Sören Andersson   +2 more
wiley   +1 more source

The Australian Penile Cancer Clinical Registry: a comprehensive national approach to data collection

BJU International, EarlyView.
Background Penile cancer is a rare malignancy, with an Australian incidence of 0.6 in 100 000 men, with a wide range of clinical presentations, from localised, curable tumours to aggressive forms with high morbidity and mortality. Epidemiological data and management guidelines for penile cancer in Australia are limited.
Henry Y.C. Pan, David Homewood, Harrison Lucas, Brendan Dittmer, Jiasian Teh, Jonathan S. O'Brien, Jianliang Liu, Ben Tran, Justin Chee, James A. Churchill, Nathan Lawrentschuk, Niall M. Corcoran   +11 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Cervical Small Cell Neuroendocrine Carcinoma Initially Detected on Cytology: Diagnostic Pitfalls and Clues

Cytopathology, EarlyView.
This case describes the initial detection of cervical small cell neuroendocrine carcinoma on conventional endometrial and cervicovaginal liquid‐based cytology. Given its rarity and high aggressiveness, early recognition and rapid, intensive treatment are crucial for improving patient outcomes.
Yesul Jeong
wiley   +1 more source