Results 91 to 100 of about 50,440 (256)

ARTISTIC: a randomised trial of human papillomavirus (HPV) testing in primary cervical screening

Health Technology Assessment, 2009
Objectives: Primary cervical screening uses cytology to detect cancer precursor lesions [cervical intraepithelial neoplasia stage 3 or beyond (CIN3+)]. Human papillomavirus (HPV) testing could add sensitivity as an adjunct to cytology or as a first test,
HC Kitchener, M Almonte, C Gilham, R Dowie, B Stoykova, A Sargent, C Roberts, M Desai, J Peto   +8 more
doaj   +1 more source

WTAP‐Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT WT1‐associated protein (WTAP), a core component of the methyltransferase complex, is involved in various tumor pathological processes, but its specific mechanism in cervical cancer (CC) remains unclear. This study, based on single‐cell transcriptomic data (including 3 CC and 2 normal tissues), constructed a CC microenvironment cell atlas ...
Ling Chen, Nuo‐Xin Hu, Zhao‐Ying Chen, Ke‐An Zhu, Wei Huang   +4 more
wiley   +1 more source

The Choice Between Definitive Radiotherapy and Surgery for Cervical Cancer With Different Histology in Current Clinical Practice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT For cervical cancer, the choice between definitive radiotherapy (RT) and surgery has long been a topic of debate. Clinical factors, including histology and tumor burden, have been examined in prior studies. Given recent advances in RT and the incorporation of concurrent chemotherapy, our study seeks to assess the optimal treatment modality for
Yu‐Lun Wu, Chen‐Wei Ho, Wen‐Shiung Liou, Chun‐Hao Yin, Jin‐Shuen Chen, Yao‐Shen Chen, Yu‐Wei Lin, Ju‐Chun Chien   +7 more
wiley   +1 more source

Occupational HPV Exposure in Otolaryngology: A Scoping Review of Detection, Risk, and Prevention

The Laryngoscope, EarlyView.
This scoping review identified 10 studies evaluating occupational HPV exposure in otolaryngology. HPV DNA was detected in surgical plume following some HPV‐related procedures, including up to 56.7% of CO2 laser plume samples, while the only study assessing oral HPV among exposed clinicians reported a prevalence of 2.2%, not exceeding that of the ...
Ying Jie Li, Alexander C. Moise, Amanda Hu   +2 more
wiley   +1 more source

HPV self-sampling in cervical cancer screening: the effect of different invitation strategies in various socioeconomic groups - a randomized controlled trial

Clinical Epidemiology, 2018
Mette Tranberg,1,2 Bodil Hammer Bech,3 Jan Blaakær,4,5 Jørgen Skov Jensen,6 Hans Svanholm,1,7 Berit Andersen1,2 1Department of Public Health Programmes, Randers Regional Hospital, Randers, Denmark; 2Department of Clinical Medicine, Aarhus ...
Tranberg M, Bech BH, Blaakær J, Jensen JS, Svanholm H, Andersen B   +5 more
doaj  

Oncologic Outcomes in p16‐Positive Oropharyngeal Squamous Cell Carcinoma With Extranodal Extension

The Laryngoscope, EarlyView.
In this retrospective cohort of 232 surgically treated patients with p16‐positive oropharyngeal squamous cell carcinoma, survival outcomes were high and recurrence rates low. Macroscopic histopathologic extranodal extension (pENE) demonstrated lower 5‐year overall survival compared to microscopic pENE (80.2% vs. 89.8%), although this difference was not
Victoria Taylor, Colin MacKay, S. Mark Taylor, Jonathan Trites, Ayham Al Afif, Adrian Mendez, Matthew H. Rigby   +6 more
wiley   +1 more source

Association between human papillomavirus infection and ocular surface squamous neoplasia in South Africa

African Vision and Eye Health
Background: Ocular surface squamous neoplasia (OSSN) is an epithelial tumour of the conjunctiva. Risk factors for developing this tumour include ultraviolet-B (UVB) exposure, human immunodeficiency virus (HIV) and human papillomavirus (HPV) infection ...
Roland Hollhumer, Susan Williams, Pamela Michelow   +2 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Nurse Navigation on Time to Postoperative Radiation Therapy after Transoral Robotic Surgery for Oropharyngeal Carcinoma

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Postoperative radiation therapy (PORT) initiation within 6 weeks of surgery is associated with improved oncologic outcomes in head and neck cancer, but delays remain common. Oncology nurse navigators (ONN) may improve care coordination.
Vera Bzhilyanskaya, Jane Y. Tong, Theresa Vetter‐Habighorst, Kelly Moyer, Jeffrey Wolf, Rodney Taylor, Jason K. Molitoris, Matthew J. Ferris, Ranee Mehra, Kyle M. Hatten   +9 more
wiley   +1 more source

The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski, H. Jeffrey Kim, Carmen C. Brewer, Sophia Martinez, Caroline Rieger, Elena Cho, David H. McDermott, Philip M. Murphy   +7 more
wiley   +1 more source