Results 111 to 120 of about 50,440 (256)

From Diagnosis to Decision‐Making: AI‐Driven Triage of Oral Mucosal Lesions Detected on Intraoral Photographs

Australian Dental Journal, EarlyView.
ABSTRACT Background Managing oral mucosal lesions in general dental practice is challenging, as visually similar conditions may require very different treatments. We developed an AI‐based triage system connecting intraoral image analysis with guideline‐based treatment recommendations, tested it externally, and compared its performance with clinicians ...
Julia Schwärzler, Ekaterina Tolstaya, Antonin Tichy, Tami Yap, Michael McCullough, Yoana Malenova, David Steybe, Sven Otto, Sebastian Paris, Falk Schwendicke   +9 more
wiley   +1 more source

Delivery mode and maternal health conditions before and after childbirth: A population‐based cohort study from Estonia

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Cesarean section is associated with higher rates of chronic health conditions and pregnancy‐related complications, whereas vaginal delivery is more commonly linked to pelvic floor and perineal complications. These findings emphasize the need for individualized decision‐making and thorough counseling about the risks and benefits of each delivery method.
Katrin Täär, Helle Karro, Merli Saare, Reedik Mägi, Estonian Biobank Research Team, Andres Metspalu, Lili Milani, Tõnu Esko, Mait Metspalu, Mari Nelis, Georgi Hudjashov, Andres Salumets, Triin Laisk, Maire Peters   +13 more
wiley   +1 more source

Focusing on VaIN2+: Development and validation of a prediction nomogram based on a large colposcopy population

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Based on data from 3259 women, this study identified older age, history of hysterectomy, specific HPV genotypes, abnormal cytology, and concurrent cervical/vulvar lesions as independent risk factors for VaIN2+ and incorporated them into a nomogram. This nomogram provides individualized VaIN2+ risk assessment to facilitate proactive identification of ...
Quanlong Lu, Yao Liu, Jing Li, Chenyao Guo, Ruifang Li, Bo Feng, Xun Gao, Lifang Gao, Zhilian Wang   +8 more
wiley   +1 more source

Myofibroblast‐Like CAFs in Metastatic Lymph Nodes Drive Tumor Stemness and Poor Prognosis in Head and Neck Cancer

Cancer Science, EarlyView.
Compared with PT‐CAFs, LN‐CAFs exhibited a myofibroblast‐like phenotype, enhanced tumor stemness‐promoting activity, and fibrosis‐, EMT‐, and hypoxia‐related transcriptomic signatures. LN‐CAF‐related gene signatures were independently associated with poor prognosis in head and neck squamous cell carcinoma.
Hiroyuki Hagiwara, Hideyuki Takahashi, Reika Kawabata‐Iwakawa, Miho Uchida, Hiroe Tada, Toshiyuki Matsuyama, Masaomi Motegi, Yuichi Tomidokoro, Kazuaki Chikamatsu   +8 more
wiley   +1 more source

Utilization of human papillomavirus testing for cervical cancer prevention in a university hospital

Cadernos de Saúde Pública, 2007
This study aimed to evaluate the performance and cost of using polymerase chain reaction (PCR) and hybrid capture in the detection of cervical intraepithelial neoplasia (CIN) in patients with cytological abnormalities (ASCUS/low-grade squamous ...
Rosekeila Simões Nomelini, Ana Cristina Macêdo Barcelos, Márcia Antoniazi Michelin, Sheila Jorge Adad, Eddie Fernando Candido Murta   +4 more
doaj  

Musashi‐1 Drives Radioresistance and Stemness in Head and Neck Squamous Cell Carcinoma via a Radioresistant FaDu Model

Cancer Science, EarlyView.
Fractionated irradiation generated radioresistant F‐IRR cells with enhanced CSC properties despite slower proliferation. MSI1 was strongly upregulated and functionally promoted stemness, tumorigenicity, and radiation resistance. JNK signaling acted upstream of MSI1, while JNK inhibition suppressed these malignant traits, identifying the JNK–MSI1 axis ...
Na‐Eun Kang, Chan‐Woong Jung, Yun‐Ju Kim, Sung‐Gil Chi, Jeong‐Yub Kim, Myung‐Jin Park   +5 more
wiley   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

Dioscin Promotes Ferroptosis in Cervical Cancer Cells via the TIGAR‐ROS Axis

Cancer Science, EarlyView.
Dioscin suppresses cervical cancer progression by promoting ferroptosis. Mechanistically, Dioscin binds to TIGAR and inhibits TIGAR function, elevating ROS levels and inducing ferroptosis. ABSTRACT Cervical cancer seriously threatens women's life and health, highlighting the urgent need for targeted therapies.
Yameng Liu, Hongli Xi, Shaoju Min, Hanlin Yang, Li Hou, Hailong Zhang, Yujie Tan   +6 more
wiley   +1 more source

Accuracy of human papillomavirus testing in detecting persistent or recurrent disease at follow-up after conization. [PDF]

Acta Obstet Gynecol Scand
Alaref G, Petersen LK.
europepmc   +1 more source

da Vinci Single‐Port Transoral Robotic Surgery in European Practice: Early Outcomes and Comparison With Transoral Laser Microsurgery

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives To report early outcomes following implementation of a da Vinci Single‐Port transoral robotic surgery (SP‐TORS) programme in the United Kingdom. To provide contextual benchmarking, outcomes were compared with a historical institutional cohort treated using transoral laser microsurgery (TLM). Design Retrospective institutional series
Matthew E. Ryan, Matthew Zammit, Kristijonas Milinis, Omar Ahmed, Rupali Sawant, Ava Gubbay, Somer Scott‐Clarkson, Harishanker Jeyarajan, Terry M. Jones, Mark Wilkie, Katharine Davies, Christopher Loh, Jason C. Fleming   +12 more
wiley   +1 more source