ABSTRACT Cervical cancer (CC) remains a major global health challenge characterized by high incidence and mortality. The histone methyltransferase suppressor of variegation 3–9 homolog 1 (SUV39H1) has emerged as a key epigenetic regulator in tumor progression, but its role in modulating pyroptosis and remodeling of the immune microenvironment in CC ...
Li Zhang +5 more
wiley +1 more source
Targeting under-screened women in cervical cancer: combining self-sampling and human papillomavirus testing with a strategic reminder plan. [PDF]
Pereira SDG +17 more
europepmc +1 more source
ABSTRACT This case reports rare cervical villoglandular adenocarcinoma metastasizing to the ovary with a deceptive borderline‐like morphology. Diagnosis relied on matching immunohistochemistry and HPV16 DNA detection in both sites. The patient underwent surgery and chemoradiotherapy, remaining recurrence‐free.
Ni Ma +4 more
wiley +1 more source
Trends in Human Papillomavirus Testing Among Patients With Oropharyngeal Cancer.
Carlson KM +10 more
europepmc +1 more source
The Utilization of Human Papillomavirus Testing for Cervical Cancer Screening in Thailand: A Comparison of Screening with and without Self-sampling Samples. [PDF]
Suwantaroj J +5 more
europepmc +1 more source
ABSTRACT The incidence of human papillomavirus‐positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost‐effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to ...
Lucas Penny +23 more
wiley +1 more source
High-risk human papillomavirus testing for underscreened populations: cost-effectiveness and affordability in three country settings. [PDF]
Sultanov M +19 more
europepmc +1 more source
ABSTRACT The human papillomavirus (HPV) life cycle is linked to epithelial cell differentiation, with viral genome amplification, E6/E7 transcription, and virion assembly spatially compartmentalized within the cervical epithelium. This organization is disrupted in transforming lesions.
Konstanze Schichl, John Doorbar
wiley +1 more source
Motivations and Preferences for Self-Sampled Human Papillomavirus Testing Among Average-and High-Risk Patients: An Exploratory Analysis. [PDF]
Morgis R +7 more
europepmc +1 more source
Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng +3 more
wiley +1 more source

