As of November 2023, 140 World Health Organization (WHO) member states had introduced human papillomavirus (HPV) vaccination in their routine immunization schedules. Despite a continuously increasing demand from countries across all income groups, supply
Helen Rees +7 more
core +1 more source
Intra-epithelial vaccination with COPV L1 DNA by particle-mediated DNA delivery protects against mucosal challenge with infectious COPV in beagle dogs. [PDF]
Protection against viral challenge with canine oral papillomavirus (COPV) was achieved by immunisation via particle-mediated DNA delivery (PMDD) of a plasmid encoding the COPV L1 gene to cutaneous and oral mucosal sites in beagle dogs.
Walcott, S. +7 more
core
E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I [PDF]
Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers of the infected epithelium.
Marchetti, Barbara +9 more
core +1 more source
Effect of Educational Program on Knowledge and Attitudes of Female Faculty Nursing Students regarding Human Papillomavirus [PDF]
Background: Human papillomavirus (HPV) is a major contributor to the occurrence of cervical cancer worldwide. Although vaccination offers effective prevention, limited awareness remains a challenge. Educating female nursing students may enhance knowledge
Hanan Ibrahim Ibrahim +2 more
doaj +1 more source
Optimising Human Papillomavirus Vaccination Strategies for Faster Cervical Cancer Elimination
ABSTRACT Aim Cervical cancer elimination is a global public health goal, with vaccination against Human Papillomavirus (HPV) and HPV screening being two major prevention pillars. This review focuses on how vaccinations can be used in order to reach the timepoint of cervical cancer elimination faster. Methods The concepts in previously published reviews
Joakim Dillner
wiley +1 more source
CCCTC-binding factor recruitment to the early region of the human papillomavirus type 18 genome regulates viral oncogene expression [PDF]
C.P. was supported by a Ph.D. studentshipfunded by the University of St. Andrews, School of Medicine. I.P. is supported by a Cancer Research UK (CRUK) Ph.D. studentship awarded to J.L.P. and S.R. I.G. and N.C.
Coleman, Nicholas +9 more
core +2 more sources
Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley +1 more source
Cellular immune responses to human papillomavirus (HPV) type 16 at the cervix of women with HPV-associated squamous intraepithelial neoplasia [PDF]
Includes bibliographical references.Cervical cancer is the most common cause of cancer-related death in black South African women. Human papillomavirus (HPV) has been found to be a necessary causative agent of cervical cancer and has been reported to be ...
Milner, Michelle
core +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Preclinical Assessment of a New Virus-like Particle-Based Quadrivalent Human Papillomavirus Vaccine in Animal Models. [PDF]
Background: A quadrivalent HPV vaccine (BPV) has been developed to prevent diseases caused by HPV types 6, 11, 16, and 18 for the first time in Iran. The BPV is composed of the papillomavirus major capsid protein L1, which serves as the primary target in
Mohammadi Barzelighi H +7 more
europepmc +2 more sources

