Phosphoprotein of Human Parainfluenza Virus Type 3 Blocks Autophagosome-Lysosome Fusion to Increase Virus Production [PDF]
Autophagy is a multistep process in which cytoplasmic components, including invading pathogens, are captured by autophagosomes that subsequently fuse with degradative lysosomes. Negative-strand RNA viruses, including paramyxoviruses, have been shown to alter autophagy, but the molecular mechanisms remain largely unknown.
Ding, Binbin +8 more
openaire +2 more sources
Summary: Background: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (
You Li, MSc +92 more
doaj +1 more source
Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah +14 more
wiley +1 more source
Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G +13 more
core
The impact of co-infection of influenza A virus on the severity of Middle East Respiratory Syndrome Coronavirus [PDF]
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A. +4 more
core +1 more source
Infecções respiratórias em crianças menores de dois anos de idade submetidas a profilaxia com palivizumabe [PDF]
OBJECTIVE: To identify the viruses involved in acute respiratory tract infections and to analyze the rates of hospitalization and death in children on palivizumab prophylaxis.METHODS:Prospective cohort of 198 infants up to one year old who were born ...
Bellei, Nancy Cristina Junqueira +4 more
core +3 more sources
Respiratory Viral Infections and the Tonsillar Transcriptome: An Exploratory Study
Clinical &Experimental Allergy, EarlyView.
Tanzeela Hanif +9 more
wiley +1 more source
This review highlights the significant burden of RSV‐associated bronchiolitis in Italian infants 0‐59 months. While RSV remains the primary pathogen, co‐infections and pandemic‐related factors have altered its epidemiological trends. ABSTRACT Background Respiratory syncytial virus (RSV) is the main cause of bronchiolitis in infants.
Angela Bechini +21 more
wiley +1 more source
Syndromic and Point-of-Care Molecular Testing [PDF]
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Abbott, April N., Relich, Ryan F.
core +1 more source
Interaction between the Nucleocapsid Protein and the Phosphoprotein of Human Parainfluenza Virus 3.
A two-hybrid system was used to study interaction in vivo between the nucleocapsid protein (NP) and the phosphoprotein (P) of human parainfluenza virus type 3 (HPIV-3).
Hong-yuan Zhao, A. Banerjee
semanticscholar +1 more source

