Results 41 to 50 of about 55,515 (211)

ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis

open access: yes, 2013
This work was supported by the Wellcome Trust.Interferon (IFN) induces an antiviral state in cells that results in alterations of the patterns and levels of parainfluenza virus type 5 (PIV5) transcripts and proteins.
Goodbourn, S   +11 more
core   +1 more source

Prevalence of laboratory markers of human respiratory viruses in monkeys of Adler primate center

open access: yesВопросы вирусологии, 2022
Introduction. The relevance of studying the circulation of human respiratory viruses among laboratory primates is associated with the need to test vaccines and antiviral drugs against these infections on monkeys.
L. I. Korzaya   +5 more
doaj   +1 more source

Can epilepsy be predicted after the first febrile seizure? Insights from machine learning of postictal EEG

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Febrile seizures (FS) are the most common seizures in childhood, yet identifying children at risk of developing epilepsy after the first FS remains challenging. We aimed to evaluate the prognostic potential of machine learning (ML) algorithms applied to post‐febrile seizure electroencephalography (EEG) recordings.
Boran Şekeroğlu   +7 more
wiley   +1 more source

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

open access: yesVeterinary Record, EarlyView.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins   +8 more
wiley   +1 more source

RNA editing in the phosphoprotein gene of the human parainfluenza virus type 3

open access: yesVirology, 1992
RNA editing of the human parainfluenza virus type 3 (HPIV3) phosphoprotein (P) gene was found to occur for the accession of an alternate discontinuous cistron. Editing occurred within a purine-rich sequence (AAUUAAAAAAGGGGG) found at the mRNA nucleotides 791-805.
Galinski, Mark S.   +2 more
openaire   +2 more sources

Modulation of immune responses by human paraininfluenza virus [PDF]

open access: yes, 2007
Human Parainfluenza virus type 3 (HPIV3) is a key respiratory pathogen responsible for bronchiolitis, pneumonia and croup. The persistent nature of this virus and its ability to reinfect within a short space of time has led to successive failures in the ...
Noone, Cariosa
core  

A fatal case of neonatal viral sepsis caused by human parainfluenza virus type 3

open access: yesVirology Journal, 2023
Background Sepsis is a systemic inflammatory response syndrome caused by severe infection in children, but cases of sepsis associated with human parainfluenza virus (HPIV) have been rarely reported in newborns.
Xiangpeng Chen   +10 more
doaj   +1 more source

Characterization of the Oligomerization Domain of the Phosphoprotein of Human Parainfluenza Virus Type 3

open access: yesVirology, 2002
The phosphoprotein (P) of human parainfluenza virus type 3 (HPIV 3) plays a central role in the viral genome RNA transcription and replication. It acts as an essential cofactor of the RNA polymerase (L) by forming a functional L-P complex, binds to the genomic N-RNA template to recruit the L-P complex for RNA synthesis, and interacts with the ...
Choudhary, Suresh K.   +4 more
openaire   +2 more sources

Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist

open access: yes, 2009
Although the Enders strain of mumps virus (MuV) encodes a functional V protein that acts as an interferon (IFN) antagonist, in multi-cycle growth assays MuV Enders grew poorly in naive ('IFN-competent' Hep2) cells but grew to high titres in 'IFN ...
Rima, B K   +15 more
core   +1 more source

Characterization of human parainfluenza virus type 3 persistent infection in cell culture [PDF]

open access: yesJournal of Virology, 1990
Three cell lines persistently infected with human parainfluenza virus type 3 were characterized on a molecular level in this study. All six structural protein genes were transcribed into monocistronic RNAs in the persistently infected cells. In both acutely and persistently infected cells, polycistronic transcripts were abundant, although the ratio of ...
A, Moscona, M S, Galinski
openaire   +2 more sources

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