Results 21 to 30 of about 1,669,866 (339)

Deep phenotyping of 11,880 highlanders reveals novel adaptive traits in native Tibetans

iScience, 2023
Summary: Tibetans are the ideal population to study genetic adaptation in extreme environments. Here, we performed systematic phenotyping of 11,880 highlanders, covering 133 quantitative traits of 13 organ systems.
Yaoxi He, Wangshan Zheng, Yongbo Guo, Tian Yue, Chaoying Cui, Ouzhuluobu, Hui Zhang, Kai Liu, Zhaohui Yang, Tianyi Wu, Jia Qu, Zi-Bing Jin, Jian Yang, Fan Lu, Xuebin Qi, Bing Su   +15 more
doaj   +1 more source

Successful naltrexone-bupropion treatment after several treatment failures in a patient with severe monogenic obesity

iScience, 2023
Summary: We describe the therapeutic journey of a 33-year-old patient with early-onset obesity (BMI 56.7 kg/m2) and hyperphagia due to a likely pathogenic heterozygous melanocortin-4 receptor (MC4R) gene variant.She was unsuccessfully treated with ...
Mila S. Welling, Mostafa Mohseni, Eline S. van der Valk, Johanna M. van Hagen, Jan Steven Burgerhart, Mieke M. van Haelst, Elisabeth F.C. van Rossum   +6 more
doaj   +1 more source

Macrophage heterogeneity in myocardial infarction: Evolution and implications for diverse therapeutic approaches

iScience
Summary: Given the extensive participation of myeloid cells (especially monocytes and macrophages) in both inflammation and resolution phases post-myocardial infarction (MI) owing to their biphasic role, these cells are considered as crucial players in ...
Babunageswararao Kanuri, Gopalkrishna Sreejit, Priosmita Biswas, Andrew J. Murphy, Prabhakara R. Nagareddy   +4 more
doaj   +1 more source

Nuclear medicine procedures and the evaluation of male sexual organs: a short review [PDF]

, 2008
Sexuality consists of three aspects that are interrelated and inseparable, biological, physiological and social. The biological aspect considers the individual's capability to give and to receive pleasure.
Adenilson de Souza da Fonseca, Bernardo-Filho M., Beutel M. E., Bouchelouche K., Chaffanjon P. C., Choe W., Dennerstein L., Fanti S., Ganjoo K. N., Gerber G., Halac M., Hatzimouratidis H., Jana S., Kevin Carter, Kim C. K., Kolodny R. C., Kotzerke J., Kotzerke J., Kumar V., Lange P. H., Mario Bernardo-Filho, Masters W. H., Orhan I., Perkins A., Perkins A., Ravizzini G., Roivainen A., Ryu J., Saha G., Sebastião David Santos-Filho, Shen Y. Y., Sotiris Missailidis, Stelzner F., Sumich A. L., Timmermans L., Tóth G., Valdés Olmos R. A., Warren G. P., Willan B. D., Zuckier L. S.   +39 more
core   +4 more sources

Mikhail Andreyevich Medvedev (to the 70^th birthday)

Бюллетень сибирской медицины, 2005
In 2005, Mikhail Andreyevich Medvedev, the honoured scientist of Russia, academician of RAMS, doctor of medical sciences, chief of normal physiology chair of the Siberian State Medical University, professor is 70.
article Editorial
doaj   +2 more sources

Validity and reliability of concept inventory test in human physiology

JPBI (Jurnal Pendidikan Biologi Indonesia)
Biology education plays a vital role in nurturing the understanding of learners about the intricacy of life. Various efforts have emerged to strengthen learning biological concepts but there were still studies that showed that learners have low mastery ...
Gio Jay B. Aligway, Jo C. Delos Angeles , Angeli V. Collano, Eljoy P. Barroca, Anna Clarissa D. Aves, Juneflor F. Catubay, Jennifer T. Edjec, Ma. Diana A. Butaya, Sylvester T. Cortes   +8 more
doaj   +1 more source

Differential proteomic patterns of plasma extracellular vesicles show potential to discriminate β-thalassemia subtypes

iScience, 2023
Summary: The observed specificity of β-thalassemia-subtype phenotypes makes new diagnostic strategies that complement current screening methods necessary to determine each subtype and facilitate therapeutic regimens for different patients.
Na Li, Bowen Wu, Jifeng Wang, Yumeng Yan, Peng An, Yuezhen Li, Yuning Liu, Yanfei Hou, Xiaoqing Qing, Lili Niu, Xiang Ding, Zhensheng Xie, Mengmeng Zhang, Xiaojing Guo, Xiulan Chen, Tanxi Cai, Jianming Luo, Fudi Wang, Fuquan Yang   +18 more
doaj   +1 more source

Paternal early experiences influence infant development through non-social mechanisms in Rhesus Macaques. [PDF]

, 2015
BackgroundEarly experiences influence the developing organism, with lifelong and potentially adaptive consequences. It has recently become clear that the effects of early experiences are not limited to the exposed generation, but can influence ...
Capitanio, John P, Kinnally, Erin L
core   +3 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Human Physiology [PDF]

, 2014
Навчально-методичний посібник побудований з урахуванням завдань навчального курсу «Фізіологія людини», передбачених програмою вищої школи для студентів небіологічних спеціальностей.
Маруненко, Ірина Михайлівна, Неведомська, Євгенія Олексіївна   +1 more
core