Results 111 to 120 of about 8,792,528 (401)

Modeling the variability of shapes of a human placenta [PDF]

, 2008
While it is well-understood what a normal human placenta should look like, a deviation from the norm can take many possible shapes. In this paper we propose a mechanism for this variability based on the change in the structure of the vascular ...
Adair, Anderson, B. Eucker, Baik, Barker, Barker, Barker, Barker, Bellingham-Young, Benirschke, Benirschke, C.M. Salafia, Charnock-Jones, Cooper, D. Haas, De Boo, Demir, Demir, Ferretti, Gerhardt, Gluckman, Grether, Hahn, J. Thorp, Jabbarzadeh, Jaddoe, Kaufmann, Kaufmann, Khong, Khong, Kingdom, Kosanke, Lawlor, Levitt, Levitt, M. Yampolsky, Masters, Mayhew, Meakin, Nilsson, O. Shlakhter, Press, Reynolds, Rich-Edwards, Rossitti, Rutland, Savitz, West, Willinger, Witten   +49 more
core   +3 more sources

Pervasive polymorphic imprinted methylation in the human placenta

Genome Research, 2016
The maternal and paternal copies of the genome are both required for mammalian development, and this is primarily due to imprinted genes, those that are monoallelically expressed based on parent-of-origin.
C. Hanna, M. Peñaherrera, Heba Saadeh, S. Andrews, D. McFadden, G. Kelsey, W. Robinson   +6 more
semanticscholar   +1 more source

Interleukin-33 in the human placenta [PDF]

The Journal of Maternal-Fetal & Neonatal Medicine, 2012
Interleukin-33 (IL-33) is the newest member of the IL-1 cytokine family, a group of key regulators of inflammation. The purpose of this study was to determine whether IL-33 is expressed in the human placenta and to investigate its expression in the context of acute and chronic chorioamnionitis.Placental tissues were obtained from five groups of ...
Vanessa Topping, Zhonghui Xu, Bing Wang, Roberto Romero, Jung-Sun Kim, Sun Young Kim, Sonia S. Hassan, Nandor Gabor Than, Chong Jai Kim, Lami Yeo, Adi L. Tarca   +10 more
openaire   +3 more sources

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Bridging the Gaps between Microplastics and Human Health

Microplastics
Given the broad and intense use of plastic, society is being increasingly affected by its degradation and by-products, particularly by microplastics (MPs), fragments smaller than 5 mm in size, and nanoplastics (NPs), with sizes less than 1 µm.
Stephanie Damaj, Farah Trad, Dennis Goevert, Jeff Wilkesmann   +3 more
doaj   +1 more source

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]

, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE, Davidge, ST, Dechend, R, Dudenhausen, JW, Geusens, N, Hering, L, Herse, F, Luft, FC, Morton, J, Muller, DN, Pijnenborg, R, Verhaegen, I, Verlohren, S   +12 more
core   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

Zika virus productively infects primary human placenta-specific macrophages.

JCI Insight, 2016
The strong association of Zika virus infection with congenital defects has led to questions of how a flavivirus is capable of crossing the placental barrier to reach the fetal brain.
K. Jurado, M. Simoni, Zhonghua Tang, Ryuta Uraki, Jesse Hwang, Sarah Householder, Ming-Jie Wu, B. Lindenbach, V. Abrahams, S. Guller, E. Fikrig   +10 more
semanticscholar   +1 more source

Resistin Is Expressed in the Human Placenta [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2003
The mechanism for decreased insulin sensitivity in pregnant women is not fully clarified. Resistin, a novel peptide hormone, is specifically expressed in the adipose tissue and decreases insulin sensitivity in rodents. In the present study, we demonstrate resistin gene expression in the human placental tissue, mainly in trophoblastic cells.
Mercy A. Nuamah, Maki Takemura, Norimasa Sagawa, Hiroaki Itoh, Kazuyo Kakui, Shigeo Yura, Shingo Fujii, Daizo Korita   +7 more
openaire   +2 more sources

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source