Advanced Materials Technologies, EarlyView.Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko +12 more
wiley +1 more source
Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA) [PDF]
, 2007 Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LCPUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues ...
Demmelmair, Hans +2 more
core +1 more source
Bridging the Gaps between Microplastics and Human Health
MicroplasticsGiven the broad and intense use of plastic, society is being increasingly affected by its degradation and by-products, particularly by microplastics (MPs), fragments smaller than 5 mm in size, and nanoplastics (NPs), with sizes less than 1 µm.
Stephanie Damaj +3 more
doaj +1 more source
Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles
Advanced Therapeutics, EarlyView.This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer +9 more
wiley +1 more source
Animal models of fetal growth restriction: Considerations for translational medicine. [PDF]
, 2015 Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity.
David, AL, Swanson, AM
core +1 more source
The art of combining neuroanatomy and microsurgical skills in modern neurosurgery
Frontiers in Neurology, 2023 Neurosurgical training outside the operating room has become a priority for all neurosurgeons around the world. The exponential increase in the number of publications on training in neurosurgery reflects changes in the environment that future ...
Juan Carlos Ahumada-Vizcaino +4 more
doaj +1 more source
NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
Advanced Science, EarlyView.This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi +16 more
wiley +1 more source
cDNA and Gene Analyses Imply a Novel Structure for a Rat Carcinoembryonic Antigen-related Protein [PDF]
, 1990 The gene encoding the human tumor marker carcinoembryonic antigen (CEA) belongs to a gene family which can be subdivided into the CEA and the pregnancy-specific glycoprotein subgroups.
Lucas, Kurt +3 more
core
N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]
, 2004 Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V. +8 more
core +1 more source
Modeling the human placental barrier to understand Toxoplasma gondii´s vertical transmission
Frontiers in Cellular and Infection Microbiology, 2023 Toxoplasma gondii is a ubiquitous apicomplexan parasite that can infect virtually any warm-blooded animal. Acquired infection during pregnancy and the placental breach, is at the core of the most devastating consequences of toxoplasmosis. T.
Paula Faral-Tello +4 more
doaj +1 more source