Results 51 to 60 of about 53,997 (201)

Efektivitas Transfusi Trombosit Hasil Uji Silang Serasi (Crossmatch) pada Kondisi Trombositopenia Refrakter

Sari Pediatri, 2018
Latar belakang. Penyebab imun tersering trombositopenia refrakter adalah adanya antibodi terhadap human leukocyte antigens (HLA) dan atau human platelet antigens (HPA).
Murti Andriastuti, Novie Amelia Chozie, Syahminar Rahmani   +2 more
doaj   +1 more source

Pesquisa de anticorpos antiplaquetários. As primeiras cem amostras estudadas.

Acta Médica Portuguesa, 2000
Two types of platelet alloantigens are considered: type I, which refers to platelet alloantigens shared by platelets and other cells; and type II, which comprises the platelet-specific alloantigens.
M M Campos, E Fernández, M J Marques, A Cordeiro   +3 more
doaj   +1 more source

In vitro expression analysis of the ITGB3 c.598G/A mutation and its association with FNAIT

Zhongguo shuxue zazhi
[Objective] To explore the role of the c.598G>A mutation of the ITGB3 gene in the occurrence of fetal and neonatal alloimmune thrombocytopenia (FNAIT) through its expression in vitro.
DING Haoqiang, YE Xin, XU Xiuzhang, XIA Wenjie, DENG Jing, LIU Jing, CHEN Yangkai, CHEN Dawei, XU Yaori   +8 more
doaj   +1 more source

Genetic variants of human platelet antigens in the Indian population from 1029 whole genomes [PDF]

, 2022
Mercy Rophina, Rahul C. Bhoyar, Mohamed Imran, Vigneshwar Senthivel, Mohit Kumar Divakar, Anushree Mishra, Bani Jolly, Sridhar Sivasubbu, Vinod Scaria   +8 more
openalex   +1 more source

Frequency of human platelet antigens in oncohematological patients with thrombocytopenia and the probability of incompatibility to platelet transfusions Frequência dos antígenos plaquetários humanos (HPA) em pacientes trombocitopênicos e predisposição à incompatibilidade transfusional

Revista Brasileira de Hematologia e Hemoterapia, 2012
OBJECTIVE: The objective of this study was to evaluate the frequencies of human platelet antigens in oncohematological patients with thrombocytopenia and to analyze the probability of their incompatibility with platelet transfusions.
Juliana Vieira dos Santos Bianchi, Maria Regina Andrade de Azevedo, Eduardo Jens, Youko Nukui, Dalton Alencar Ficher Chamone   +4 more
doaj   +1 more source

Immunological platelet transfusion refractoriness: current insights from mechanisms to therapeutics

Platelets
Although there have been tremendous improvements in the production and storage of platelets, platelet transfusion refractoriness (PTR) remains a serious clinical issue that may lead to various severe adverse events.
Xiaoyu Chen, Yuhong Zhao, Yan Lv, Jue Xie   +3 more
doaj   +1 more source

Development of quantitative monoclonal antibody-specific immobilization of platelet antigens assay for antibodies against human platelet antigen-1a, 3a, and 5b

Platelets, 2018
Human platelet antigens (HPAs) are platelet-specific alloantigens that cause alloimmunization. Alloantibodies induced via pregnancy and transfusion may result in various clinical syndromes.
R.S. Li, B. Ling, P. Lu
doaj   +1 more source

Novel method for simultaneously detecting HPA and HLA antibodies using Luminex microbeads

Journal of Translational Medicine, 2019
Background Alloantibodies against human platelet antigens (HPAs) and human leukocyte antigen (HLA) are implicated in several immune-mediated platelet disorders.
Sudan Tao, Shu Chen, Xiaozhen Hong, Ji He, Faming Zhu   +4 more
doaj   +1 more source

Human platelet antigen 1-6, 9 and 15 in the Iranian population: An anthropological genetic analysis [PDF]

, 2020
Mohammad Hossein Kazemi, Farideh Malakootikhah, Zahra Momeni-Varposhti, Reza Falak, Ali‐Akbar Delbandi, Nader Tajik   +5 more
openalex   +1 more source

Platelet compatibility and platelet antibodies detection: A step towards resolving dilemma in management of platelet refractoriness in oncology patients

Global Journal of Transfusion Medicine, 2019
Background: Platelet refractoriness complicates the provision of platelet transfusions- a critical and essential part in management of thrombocytopenia in Oncology patients. Platelet refractoriness poses challenge due to alloimmunization to HLA (Class I)
Sadhana Mangwana, Atin Kacker, Nikhil Simon   +2 more
doaj   +1 more source