Results 91 to 100 of about 5,283,554 (314)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
INFAD, 2018 The aim of this study was to know the indicators of employability and satisfaction with training in a Higher Education Institution (HEI) in a sample of 1693 graduates, with a mean of 29.05 years of age (Dp7,67). Statistical analysis was performed through
Sónia Brito Costa +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Review on probiotic potential in human health, aquaculture and animal feed
, 2019 Probiotics, a term that means ―promoting life‖ where living microbes function to regulate the microbiota of a host body compartment. Hence, it conferring health-promoting activities to the host.
Abdul Manas, N. H. +4 more
core
Move Your Body: Engaging Museum Visitors with Human-Data Interaction
, 2020 Museums have embraced embodied interaction: its novelty generates buzz and excitement among their patrons, and it has enormous educational potential. Human-Data Interaction (HDI) is a class of embodied interactions that enables people to explore large ...
Kankara, Sreekanth R. +9 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Analysis of Human Development in Hyderabad Karnataka Region
, 2020 The economic growth model of advancement had challenged by the UNDP in its first Human Development Report 1990 which emphasized that individuals not things are the abundance of countries and it is they who ought to be the focal point of an ...
Dr. Basavaraj S Benni +1 more
core
, 2020 Technological and social evolutions have prompted operational, phenomenological, and ontological shifts in communication processes. These shifts, we argue, trigger the need to regard human and machine roles in communication processes in a more ...
Jaime Banks +6 more
core +1 more source
Comprehensive PsychiatryBackground: Fire and emergency services personnel face unique occupational hazards, including repeated exposure to potentially psychologically traumatic events (PPTEs), which can impact their mental health.
Lisa Mackay +4 more
doaj +1 more source