Results 81 to 90 of about 1,083,262 (314)

A meaningful workplace: Framework, space and context

HTS Teologiese Studies/Theological Studies, 2013
An attempt was made to describe and to eventually implement work space that can be defined as psychologically meaningful and which has increased during the past 5−10 years.
Petrus L. Steenkamp, Johan S. Basson
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Managing diversity in Israel: Some applications for South Africa

South African Journal of Economic and Management Sciences, 1999
The management of diversity manifests itself in a very specific way in Israeli society. This is so because the management process occurs at two levels: a national-political level (first order processes) and the individual enterprise level (second order ...
R. J. Petersen, L. P. Vermeulen
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

BRIDGING THE FIELDS OF INNOVATIVE BEHAVIOUR AND HUMAN RESOURCE MANAGEMENT: A SYSTEMATIC REVIEW AND FUTURE RESEARCH DIRECTIONS

, 2014
Research has underlined the importance of Individual Innovative Behaviour or Innovative Work Behaviour (IWB) for firms’ success and long term survival.
TINTORRI S., Tintorri, Sara, BONESSO, Sara, BONESSO S.   +3 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The impact of team knowledge sharing and change capabilities on team performance in policing: A team-level analysis

European Research on Management and Business Economics
Grounded in the theoretical perspective of shared mental models, this study examines how team knowledge sharing influences team performance through team change capability.
Agung Kurnia Putra, Wahyu Eko Pujianto, Mohammad Fakhruddin Mudzakkir, Fendy Suhariadi, Juansih   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Empowering women can increase modern contraception use among women with no fertility intentions in South Asia

Women's Health
Background: The relationship between women’s empowerment and modern contraception utilization is well documented; however, they focused on all reproductive-aged women and lacked dimensions of empowerment.
Mahmudul Hasan Tonmoy, Raufun Hasan Arnob, Shamima Akter, Md. Mosfequr Rahman   +3 more
doaj   +1 more source

Manufacturing More Effective TQM: Implications for the Management of Human Resources

, 1994
This paper examines the issue of Total Quality Management (TQM) and the management of human resources. It suggests that while TQM has been identified as a major innovation in management practice, there has been a preoccupation with the "hard" production ...
Marchington, Mick, Wilkinson, Adrian, Dale, Barrie   +2 more
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