Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
QUALITY – AN ATTRIBUTE OF A TERRITORY’S DEVELOPMENT IN THE CONTEXT OF SUSTAINABLE DEVELOPMENT [PDF]
Sustainability starts from the idea that human activities are dependent on environment and resources. Health, social security and economic stability of society are essential in defining quality of life.
Gabriela BOLOGA, Marin BURTIC?
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
HUMAN RESOURCES MOTIVATION - A CHALLENGE FOR SMES ECONOMIC PERFORMANCES [PDF]
The present research aims to establish and configurate human resources development strategies for the employees of small and medium-sized enterprises (SMEs) that activate in the tourism field of activity (hotels and other accomodation establishments ...
CHIVU Iulia +3 more
core
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Перспективи соціально-економічного розвитку людських ресурсів в умовах глобалізації [PDF]
PROSPECTS OF HUMAN RESOURCES SOCIAL AND ECONOMIC DEVELOPMENT UNDER THE CONDITIONS OF GLOBALIZATION In the article the determining moving forces of human resources social and economic development have been emphasised. The impact of globalization
Sardak, Sergii
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
El presente estudio tuvo como objetivo generar una aproximación a un modelo de gerencia educativa para la III etapa de Educación Básica y Media-Diversificada y Profesional considerando las dimensiones comunicativa, técnica, de participación y de ...
Elda María Rodríguez
doaj
Employee green behavior: Bibliometric-content analysis
Purpose: – This research conducted a thorough literature review to analyze current research on Employee Green Behavior (EGB) and its contexts. It identified key areas of emphasis in EGB and provided a precise roadmap for future research.
Xinxin Zhang +2 more
doaj +1 more source

