Results 1 to 10 of about 133,059 (156)

Human Respiratory Syncytial Virus Subgroup A and B Infections in Nasal, Bronchial, Small-Airway, and Organoid-Derived Respiratory Cultures

mSphere, 2021
Human respiratory syncytial virus (HRSV) is the major cause of bronchiolitis and pneumonia in young infants and causes almost 200,000 deaths per year.
L. C. Rijsbergen, M. M. Lamers, A. D. Comvalius, R. W. Koutstaal, D. Schipper, W. P. Duprex, B. L. Haagmans, R. D. de Vries, R. L. de Swart   +8 more
doaj   +2 more sources

Severe respiratory disease caused by human respiratory syncytial virus impairs language learning during early infancy

Scientific Reports, 2020
Human respiratory syncytial virus infection is a leading cause of pediatric morbidity and mortality. A previous murine study showed that during severe acute respiratory infections the virus invades the central nervous system, and that infected animals ...
Marcela Peña, Cristina Jara, Juan C. Flores, Rodrigo Hoyos-Bachiloglu, Carolina Iturriaga, Mariana Medina, Javier Carcey, Janyra Espinoza, Karen Bohmwald, Alexis M. Kalergis, Arturo Borzutzky   +10 more
doaj   +2 more sources

Human Respiratory Syncytial Virus and Influenza Seasonality Patterns—Early Findings From the WHO Global Respiratory Syncytial Virus Surveillance

Influenza and Other Respiratory Viruses, 2020
Human respiratory syncytial virus (RSV) causes illnesses among all age groups and presents a burden to healthcare services. To better understand the epidemiology and seasonality of RSV in different geographical areas, the World Health Organization (WHO ...
Joanna Ellis, Shobha Broor, Florette Kathleen Treurnicht   +2 more
exaly   +2 more sources

Viral N 6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Nature Communications, 2019
Here, Xue et al. identify N 6-methyladenosine (m6A) modification sites in RNAs of respiratory syncytial virus (RSV) and show that these sites, particularly sites in the transcript encoding for the viral glycoprotein, affect virus replication in primary ...
Miaoge Xue, Boxuan Simen Zhao, Zijie Zhang, Mijia Lu, Olivia Harder, Phylip Chen, Zhike Lu, Anzhong Li, Yuanmei Ma, Yunsheng Xu, Xueya Liang, Jiyong Zhou, Stefan Niewiesk, Mark E. Peeples, Chuan He, Jianrong Li   +15 more
doaj   +2 more sources

Standardized Phylogenetic Classification of Human Respiratory Syncytial Virus below the Subgroup Level. [PDF]

Emerg Infect Dis
A globally implemented unified phylogenetic classification for human respiratory syncytial virus (HRSV) below the subgroup level remains elusive. We formulated global consensus of HRSV classification on the basis of the challenges and limitations of our ...
Goya S, Ruis C, Neher RA, Meijer A, Aziz A, Hinrichs AS, von Gottberg A, Roemer C, Amoako DG, Acuña D, McBroome J, Otieno JR, Bhiman JN, Everatt J, Muñoz-Escalante JC, Ramaekers K, Duggan K, Presser LD, Urbanska L, Venter M, Wolter N, Peret TCT, Salimi V, Potdar V, Borges V, Viegas M.   +25 more
europepmc   +2 more sources

EDP-938, a Respiratory Syncytial Virus Inhibitor, in a Human Virus Challenge

New England Journal of Medicine, 2022
BACKGROUND Respiratory syncytial virus (RSV) infection causes substantial morbidity and mortality among infants, older adults, and immunocompromised adults.
Alaa Ahmad, Nathalie Adda, Nicolas Noulin   +2 more
exaly   +2 more sources

Advances in Detection Methods for Human Respiratory Syncytial Virus Neutralizing Antibodies [PDF]

Vaccines
Human respiratory syncytial virus (HRSV) is a major cause of severe lower respiratory tract infections in infants, young children, and older adults worldwide.
Qi Shen, Jing Gai, Yanqiu Zhou
doaj   +2 more sources

Human Respiratory Syncytial Virus in Vaccinated and Unvaccinated Adults, Georgia, USA, 2024–2025 [PDF]

Emerging Infectious Diseases
We analyzed respiratory syncytial virus genome sequences from adults in Georgia, USA, during 2024–2025. We found multiple co-circulating lineages of both A and B subtypes.
Saïd Rachida, Alaa Ahmed, Diana Rojas-Gallardo, Henok Tafesse, Hannah Dakanay, Mackenzie Duford, Collin Tolbert, Ryan S. Springfield, Anne Piantadosi   +8 more
doaj   +2 more sources

Induction of DNA Double-Strand Breaks and Cellular Senescence by Human Respiratory Syncytial Virus

Virulence, 2016
Human respiratory syncytial virus (HRSV) accounts for the majority of lower respiratory tract infections during infancy and childhood and is associated with significant morbidity and mortality.
Alberto Zambrano, Ana Aranda, Isidoro Martínez   +2 more
exaly   +2 more sources

Genomic Epidemiology of Human Respiratory Syncytial Virus, Minnesota, USA, July 2023–February 2024 [PDF]

Emerging Infectious Diseases
We recently expanded the viral genomic surveillance program in Minnesota, USA, to include human respiratory syncytial virus. We performed whole-genome sequencing of 575 specimens collected at Minnesota healthcare facilities during July 2023–February ...
Daniel Evans, Henry Kunerth, Erica Mumm, Sarah Namugenyi, Matthew Plumb, Sarah Bistodeau, Scott A. Cunningham, Bryan Schmitt, Karen Martin, Katherine Como-Sabetti, Ruth Lynfield, Xiong Wang   +11 more
doaj   +2 more sources