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Update on human respiratory syncytial virus
Clinical Microbiology Newsletter, 2001Abstract Since its initial discovery 50 years ago, RSV has continued to generate strong and sustained efforts in the scientific and health care communities to develop modalities for prevention and treatment. Further studies that define the molecular evolution of RSV and the mechanisms by which it evades the immune response should facilitate the ...
Nahed Ismail, Barbara Reisner
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Human respiratory syncytial virus and Th1 chemokines.
La Clinica terapeutica, 2015The importance of the Type-1 helper (Th1) chemokines in RSV (respiratory syncytial virus) infection has been shown by several studies, in animal models, and in humans. The production of Th1 chemokines within the lower respiratory tract has been shown in patients with RSV bronchiolitis, particularly chemokine (C-X-C motif) ligand (CXCL)10/interferon-γ ...
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Comparison of the seroprevalence of human metapneumovirus and human respiratory syncytial virus
Journal of Medical Virology, 2003Abstract Human metapneumovirus (hMPV) is a virus that induces human respiratory syncytial virus (hRSV)‐like illnesses, ranging from upper respiratory tract infection to severe bronchiolitis and pneumonia. The 100 serum samples from children aged 1 month to 5 years were tested for the presence of hMPV and hRSV ...
Takashi, Ebihara +5 more
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Respiratory Syncytial Virus and Human Metapneumovirus
2015Respiratory syncytial virus (RSV) is one of the most vulnerable pathogens to environmental changes. RSV is the major cause of lower respiratory tract illnesses such as bronchiolitis, tracheobronchitis, and pneumonia among infants and young children worldwide.
N. Esther Babady, Yi-Wei Tang
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Pharmacological management of human respiratory syncytial virus infection
Expert Opinion on Pharmacotherapy, 2020Human respiratory syncytial virus (hRSV) is the primary viral cause of respiratory diseases, leading to bronchiolitis and pneumonia in vulnerable populations. The only current treatment against this virus is palliative, and no efficient and specific vaccine against this pathogen is available.The authors describe the disease symptoms caused by hRSV, the
Alexis M. Kalergis +6 more
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Purification of human respiratory syncytial virus fusion glycoprotein
Protein Expression and Purification, 2012Human respiratory syncytial virus (RSV) fusion glycoprotein (F) elicits neutralizing antibodies to RSV and has therefore attracted much attention as a suitable candidate antigen in the development of gene-based vaccines against RSV infections. However, a major obstacle in vaccine development has been the problem of antigen purification. To address this
Yanpeng, Zheng +5 more
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Respiratory syncytial virus interaction with human airway epithelium
Trends in Microbiology, 2013Although respiratory syncytial virus (RSV) is a major human respiratory pathogen, our knowledge of how it causes disease in humans is limited. Airway epithelial cells are the primary targets of RSV infection in vivo, so the generation and exploitation of RSV infection models based on morphologically and physiologically authentic well-differentiated ...
Villenave, Remi +2 more
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Respiratory syncytial virus infections in human beings and in cattle
Journal of Infection, 1994Respiratory syncytial virus (RSV) causes yearly outbreaks of respiratory disease in human beings and cattle all over the world. Most severe human respiratory syncytial virus (HRSV)-associated disease is observed in children less than 1 year of age while most severe bovine respiratory syncytial virus (BRSV)-associated disease is observed in calves less ...
W H, Van der Poel +3 more
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Antigenic and genetic variation in human respiratory syncytial virus
Pediatric Infectious Disease Journal, 2004Human respiratory syncytial virus (HRSV) is a leading cause of serious pediatric respiratory disease worldwide. Natural infection provides only partial protection as repeat infections occur throughout life. A brief review of the extent of antigenic and genetic variation observed in HRSV clinical isolates is presented.Recent experimental research is ...
Gail W, Wertz, Robin M, Moudy
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[Illnesses by the human respiratory syncytial virus].
Medizinische Monatsschrift fur Pharmazeuten, 2006Human respiratory syncytial virus (HRSV) is a single-stranded, enveloped RNA virus of the Paramyxoviridae family. Worldwide, HRSV represents the leading cause of respiratory tract infections in infants and young children. Approximately up to 70% of infants are infected during their first year of life.
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