Results 31 to 40 of about 10,361 (137)

Epidemiology and clinical manifestations of different enterovirus and rhinovirus types show that EV‐D68 may still have an impact on severity of respiratory infections

open access: yesJournal of Medical Virology, Volume 94, Issue 8, Page 3829-3839, August 2022., 2022
Abstract Respiratory infections are often caused by enteroviruses (EVs). The aim of this study was to identify whether certain types of EV were more likely to cause severe illness in 2016, when an increasing spread of upper respiratory infections was observed in Gothenburg, Sweden.
Simon B. Larsson   +4 more
wiley   +1 more source

Analysis of Paramyxovirus Transcription and Replication by High-Throughput Sequencing. [PDF]

open access: yes, 2019
We have developed a high-throughput sequencing (HTS) workflow for investigating paramyxovirus transcription and replication. We show that sequencing of oligo(dT)-selected polyadenylated mRNAs, without considering the orientation of the RNAs from which ...
Davison, AJ   +6 more
core   +4 more sources

Application of shotgun metagenomics sequencing and targeted sequence capture to detect circulating porcine viruses in the Dutch–German border region

open access: yesTransboundary and Emerging Diseases, Volume 69, Issue 4, Page 2306-2319, July 2022., 2022
Abstract Porcine viruses have been emerging in recent decades, threatening animal and human health, as well as economic stability for pig farmers worldwide. Next‐generation sequencing (NGS) can detect and characterize known and unknown viruses but has limited sensitivity when an unbiased approach, such as shotgun metagenomics sequencing, is used.
Leonard Schuele   +10 more
wiley   +1 more source

Canine distemper virus in wildlife in south‐western Europe

open access: yesTransboundary and Emerging Diseases, Volume 69, Issue 4, Page e473-e485, July 2022., 2022
Abstract Multi‐host pathogens emerging and re‐emerging at the wildlife–domestic animal interface affect wildlife management and conservation. This is the case of canine distemper virus (CDV), a paramyxovirus closely related to human measles virus and rinderpest virus of cattle.
Álvaro Oleaga   +8 more
wiley   +1 more source

Multicenter evaluation of the QIAstat Respiratory Panel-A new rapid highly multiplexed PCR based assay for diagnosis of acute respiratory tract infections.

open access: yesPLoS ONE, 2020
Acute respiratory tract infections (ARTI), including the common cold, pharyngitis, sinusitis, otitis media, bronchiolitis and pneumonia are the most common diagnoses among patients seeking medical care in western countries, and account for most ...
Marijo Parčina   +5 more
doaj   +1 more source

Human IFIT1 inhibits mRNA translation of rubulaviruses but not other members of the Paramyxoviridae family [PDF]

open access: yes, 2016
This work was supported by The Welcome Trust (101788/Z/13/Z, 101792/Z/13/Z) and Medical research council grant (G1100110/1, MR/K024213/1).We have previously shown that IFIT1 is primarily responsible for the antiviral action of interferon (IFN) alpha/beta
Andrejeva, J.   +7 more
core   +4 more sources

An approach to the control of disease transmission in pig-to-human xenotransplantation. [PDF]

open access: yes, 2000
: Although several major immunologic hurdles need to be overcome, the pig is currently considered the most likely source animal of cells, tissues and organs for transplantation into humans.
A. D. M. E. Osterhaus   +57 more
core   +4 more sources

The cystic fibrosis microbiome in an ecological perspective and its impact in antibiotic therapy [PDF]

open access: yes, 2016
The recent focus on the cystic fibrosis (CF) complex microbiome has led to the recognition that the microbes can interact between them and with the host immune system, affecting the disease progression and treatment routes.
A Bragonzi   +159 more
core   +1 more source

Comprehensive Detection of Candidate Pathogens in the Lower Respiratory Tract of Pediatric Patients With Unexpected Cardiopulmonary Deterioration Using Next-Generation Sequencing [PDF]

open access: yes, 2020
Objectives: Next-generation sequencing has been applied to the investigation of microorganisms in several clinical settings. We investigated the infectious etiologies in respiratory specimens from pediatric patients with unexpected cardiopulmonary ...
103497   +21 more
core   +1 more source

Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization [PDF]

open access: yes, 2023
The protein C is a small viral protein encoded in an overlapping frame of the P gene in the subfamily Orthoparamyxovirinae. This protein, expressed by alternative translation initiation, is a virulence factor that regulates viral transcription ...
Baudin, Florence   +10 more
core   +1 more source

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