Results 141 to 150 of about 12,497,859 (378)
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Support of Epidemiological Well-Being during Regional Event with the International Participation
Эпидемиология и вакцинопрофилактика, 2016 Role of regional cultural mass events as potential threats for epidemics of the dangerous infectious diseases associated with implementation of external and internal epidemiological risks is demonstrated.
A. K. Noskov +6 more
doaj +1 more source
Human Indignity: From Legal AI Personhood to Selfish Memes [PDF]
arXiv, 2018 It is possible to rely on current corporate law to grant legal personhood to Artificially Intelligent (AI) agents. In this paper, after introducing pathways to AI personhood, we analyze consequences of such AI empowerment on human dignity, human safety and AI rights.
arxiv
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Do LLMs exhibit demographic parity in responses to queries about Human Rights? [PDF]
arXivThis research describes a novel approach to evaluating hedging behaviour in large language models (LLMs), specifically in the context of human rights as defined in the Universal Declaration of Human Rights (UDHR). Hedging and non-affirmation are behaviours that express ambiguity or a lack of clear endorsement on specific statements.
arxiv
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source