Results 141 to 150 of about 38,094,648 (298)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

MANF is essential for astrocyte survival in the monkey brain. [PDF]

Protein Cell
Xing T, Chen L, Duan X, Zhang Y, Qin Y, Lin J, Ruan E, Guo T, Ye C, He J, Xie S, Zhang J, Song X, Huang W, Li B, Yang W, Li S, Li XJ, Yang S.   +18 more
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Full Issue, Volume 2, Number 1

Journal of Human Sciences and Extension, 2014
Journal of Human Science and Extension
doaj  

RETRACTED: Abou-ElNaga et al. Novel Nano-Therapeutic Approach Actively Targets Human Ovarian Cancer Stem Cells After Xenograft into Nude Mice. <i>Int. J. Mol. Sci.</i> 2017, <i>18</i>, 813. [PDF]

Int J Mol Sci
Abou-ElNaga A, Mutawa G, El-Sherbiny IM, Abd-ElGhaffar H, Allam AA, Ajarem J, Mousa SA.   +6 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Full Issue, Volume 1, Number 2

Journal of Human Sciences and Extension, 2013
Journal of Human Science and Extension
doaj  

Human Movement Science The Trondheim Model

Uniped, 1994
HTA Whiting, R. Ingvaldsen
doaj   +1 more source

Workforce Science and the Human-AI economy of health and care. [PDF]

PLOS Glob Public Health
Campbell J.
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source