The long arc of scientists in spaceflight: scientists flying with their experiments. [PDF]
Ferl RJ.
europepmc +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Information Management Policy - King Abdullah University of Science and Technology
Records, Information and Archies Management Policy of King Abdullah University of Science and TechnologyRecords, Information and Archives Management Policy of King Abdullah University of Science and ...
King Abdullah University of Science and Technology
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RETRACTED: Kim et al. Anthocyanins Derived from <i>Vitis coignetiae Pulliat</i> Contributes Anti-Cancer Effects by Suppressing NF-κB Pathways in Hep3B Human Hepatocellular Carcinoma Cells and In Vivo. <i>Molecules</i> 2020, <i>25</i>, 5445. [PDF]
Kim MJ +11 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
CRISPR screening identifies GNPTAB as a noncanonical STING activator driving cellular senescence. [PDF]
Yin J +16 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Retraction Note: α-Ketoglutarate dictates AMPK protein synthesis for energy sensing in human cancers. [PDF]
Mi W +21 more
europepmc +1 more source

