Results 171 to 180 of about 8,954,431 (357)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Full Issue, Volume 2, Number 1

open access: yesJournal of Human Sciences and Extension, 2014
Journal of Human Science and Extension
doaj  

Conversations at the crossroads of the Human RNome Project: a collaborative reflection by the RNome Early Career Researchers. [PDF]

open access: yesRNA Biol
Henzeler B   +5 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Full Issue, Volume 1, Number 2

open access: yesJournal of Human Sciences and Extension, 2013
Journal of Human Science and Extension
doaj  

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