Results 91 to 100 of about 6,838,489 (312)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
New approaches for estimating risk from exposure to diethylstilbestrol. [PDF]
, 1999 A subgroup from a National Institute of Environmental Health Sciences, workshop concerned with characterizing the effects of endocrine disruptors on human health at environmental exposure levels considered the question, If diethylstilbestrol (DES) were ...
Cunha, GR +7 more
core +2 more sources
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Allameh Tabatabai's credit theory and its mediating role between transcendental wisdom and human sciences [PDF]
حکمت اسراPhilosophy is the basic theory of human and social sciences, and transcendental wisdom, as a philosophical system, has the capacity to realize this basic structure.
Hamed Esmaeilzadeh +2 more
doaj +1 more source
Editorial: ecopsychology: past, present and future [PDF]
, 2010 Opening paragraph: One of the central tenets of ecopsychology is the articulation and examination of our psychological, including the emotional, relationships with the natural world.
Jordan, Martin +2 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The epistemological validity of suspicion and its impact on the evolution of human sciences [PDF]
حکمت اسراOne of the main topics in the science of the principles of suspicion, such as single news, the authority of appearances, etc. Most of the issues raised in the authenticity of suspicion are raised with a principled approach, and its epistemological value ...
Naiemeh Najmi Nejad +2 more
doaj +1 more source
Beyond Quality in Early Childhood Education and Care – Languages of Evaluation [PDF]
Bildung, Kinder, Pädagogik, Bildungspolitik, Bildungsinvestition, Education, Children, Education sciences, Educational policy, Human capital ...
Gunilla Dahlberg, Peter Moss
core
Human sciences and divine sciences [PDF]
, 2013 Se discutió acerca de la compatibilidad entre la omnisciencia de Dios y la libertad humana. La concordia entre el determinismo de la ciencia y la libertad de los sujetos viene siendo también objeto de polémica en la filosofía de las ciencias sociales del
Alvargonzález, David
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source