Results 31 to 40 of about 7,638,508 (295)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Evaluating thermal comfort indices for outdoor spaces on a university campus

Scientific Reports
This study evaluates the applicability of three thermal comfort indices—Physiologically Equivalent Temperature (PET), Standard Effective Temperature (SET), and Universal Thermal Climate Index (UTCI)—in various outdoor environments on the campus of Xi’an ...
Wenqiang Jing, Zeming Qin, Teng Mu, Zhemin Ge, Yuting Dong   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Environmental Effects from Pocket Park Design According to District Planning Patterns—Cases from Xi’an, China

Atmosphere, 2022
Rapid urban expansion leads to the continuous deterioration of the urban thermal environment, which endangers the sustainable development of the city; meanwhile, countries all over the world are becoming increasingly interested in the mitigating effects ...
Jiajie Hou, Yupeng Wang, Dian Zhou, Zhe Gao   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A study on analysing sociospatial distribution and equity in access to urban parks in Bengaluru, India

The Lancet Planetary Health
Background: Given the effect of urbanisation on land use, allocation, and implementation of urban green spaces, we attempt to analyse the sociospatial distribution and equity in access to urban parks in Bengaluru, India, also known as the garden city of ...
Nilanjan Bhor, MPH, Dhananjayan Mayavel, MTech   +1 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

UN-Habitat (United Nations Human Settlements Programme) - Global Report on Sanitation and Wastewater Management in Cities and Human Settlements

, 2023
This Global Report on Sanitation and Wastewater Management in Cities and Human Settlements is a global reference on sanitation and wastewater in urban settings.
Kossi Sossou, Seyram, Ily, Jean-Marie, Magawa, Yvonne, Anderson Andrianisa, Harinaivo, Drabble, Sam, Jabagi, Elise, White, Zach, Mansour, Goufrane, Campos, Luiza, Ahossouhe, Mahugnon Samuel, Nguyet Anh, Pham, Koch, Marta, Owako, Emanuel, Parikh, Priti, Thapa, Kushma, Saker, Analia, Mabia, Asengo Gerardin, Saha, Pritum, Thi Thuy, Bui   +18 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Investigation on Influence of Friction Plate Material Properties on Hysteretic Performance and Stability of Friction Dampers

Buildings
Friction dampers are widely used in building seismic protection due to their excellent shock-absorbing performance and reliable operation. To clarify the influence of friction plate material properties on the hysteretic behavior and stability of friction
Fengzhe Jiang, Guangyu Xu, Jianping Liu, Shaohui Dang, Zahid Irshad, Yanchao Yue, Chen Guo   +6 more
doaj   +1 more source