Results 41 to 50 of about 426,418 (303)

Sunlight perception and outdoor thermal comfort in college campuses: a new perspective

open access: yesScientific Reports, 2023
The thermal comfort of outdoor spaces in colleges and universities is crucial for promoting outdoor activities and relieving psychological pressure. To evaluate outdoor thermal comfort from a new perspective, this study investigated subjects' sunlight ...
Shaobo Ning, Wenqiang Jing, Zhemin Ge
doaj   +1 more source

Geospatial multi-criteria analysis for identifying high priority clean energy investment opportunities: A case study on land-use conflict in Bangladesh [PDF]

open access: yes, 2019
Bangladesh is a globally important emerging economy with rapidly increasing energy demand. The Bangladeshi government's primary capacity expansion plan is to install 13.3 GW of new coal by 2021, including the 1.3 GW Rampal coal power plant to be ...
Kammen, DM, Shiraishi, K, Shirley, RG
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Climate change impacts on migration and labour market [PDF]

open access: yes, 2012
Floods, droughts and monsoons have always disturbed human settlements, but there are more settlements now and more people in the world. Therefore, if a natural disaster happens, more will suffer than ever before.
Losonc, Krisztina
core  

Factors of land abandonment in mountainous Mediterranean areas : the case of Montenegrin settlements [PDF]

open access: yes, 2016
Land use changes have been investigated in the surroundings of 14 rural Montenegrin settlements in order to get specific information about trends in land abandonment since around 1950. Permanently, seasonally and less inhabited settlements with different
Kerckhof, Annelies   +3 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Interfaces of ‘being healthy and being Ill’: how is health being perceived by individuals with non-communicable chronic conditions?

open access: yesInternational Journal for Equity in Health
Background Accommodating chronic care into the everyday lives of individuals diagnosed with non-communicable chronic conditions often poses significant challenges.
Nilanjan Bhor, P Omkar Nadh
doaj   +1 more source

Assessing texture pattern in slum across scales: an unsupervised approach [PDF]

open access: yes, 2005
According to the Global Report on Human Settlements (United Nations, 2003), almost 1 billion people (32% of the world ’s population) live in squatter settlements or slums.
Barros Filho, M., Sobreira, F.
core  

Home - About - Disclaimer - Privacy