Results 91 to 100 of about 9,029,134 (304)

Vitamin D and Human Skeletal Muscle [PDF]

Scandinavian Journal of Medicine & Science in Sports, 2009
Vitamin D deficiency is an increasingly described phenomenon worldwide, with well-known impacts on calcium metabolism and bone health. Vitamin D has also been associated with chronic health problems such as bowel and colonic cancer, arthritis, diabetes and cardiovascular disease.
openaire   +2 more sources

Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus [PDF]

, 1996
The myosin light-chain 1/3 locus (MLC1/3) is regulated by two promoters and a downstream enhancer element which produce two protein isoforms in fast skeletal muscle at distinct stages of mouse embryogenesis. We have analyzed the expression of transcripts
McGrew, M J; id_orcid, Hasegawa, K, Bogdanova, N, Kitsis, R N, Rosenthal, N, Hughes, S H   +5 more
core  

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy [PDF]

, 2013
BACKGROUND: Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass ...
Handschin, Christoph, Bentzinger, C. Florian, Guridi, Maitea, Castets, Perrine, Hall, Michael N, Tintignac, Lionel A., Hall, Michael N., Perrine Castets, Romanino, Klaas, Tintignac, Lionel, Rüegg, Markus A, Michael N Hall, Lin, Shuo, Markus A Rüegg, Bentzinger, C Florian, Christoph Handschin, Serge Summermatter, Summermatter, Serge, C Bentzinger, Klaas Romanino, Maitea Guridi, Shuo Lin, Rüegg, Markus A., Lionel A Tintignac, Lin S, Castets P, Rüegg MA, Bentzinger CF, Tintignac, Lionel A, Guridi M, Tintignac LA, Summermatter S, Hall MN, Romanino K, Handschin C   +34 more
core   +1 more source

Coordinated Architectural and Chemical Reinforcement in the Crushing Mandible of a Soldier Termite

Advanced Functional Materials, EarlyView.
The crushing mandible of a soldier termite withstands substantial biting loads despite lacking mineral. Its cuticle is partitioned: convex teeth pair hardness and zinc enrichment with aligned chitin fibers for contact durability, while stiffer concave regions between teeth carry bending loads.
Andrew Tran Nguyen, Patryk Wąsik, Juan Fernando Cucuyame Morales, Marie Kate Palau, Adrian Francisco Duran Ornelas, Phani Saketh Dasika, Jin Hee Kim, Radhika Laxminarayana, Eric Hintsala, Greta Chang, Junzhi Liao, Lizhi Sun, Nathan Lord, Atsushi Arakaki, Paul Bardunias, Pablo Zavattieri, David Kisailus   +16 more
wiley   +1 more source

LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force

, 2019
Background: Skeletal muscle mass and strength are crucial determinants of health. Muscle mass loss is associated with weakness, fatigue, and insulin resistance.
Cheng, Arthur J.,, Chaillou, Thomas,, Martínez-Redondo, Vicente,, Izadi, Manizheh,, Porsmyr-Palmertz, Margareta,, Ruas, Jorge L,, Lanner, Johanna T.,, Hansson, Alicia,, Cervenka, Igor,, Agudelo, Leandro Z.,, Nair, K. Sreekumaran,, Estall, Jennifer L.,, Ferreira, Duarte M. S.,, Robinson, Matthew M.,, Valente-Silva, Paula,, Correia, Jorge C.,, Pettersson-Klein, Amanda T.,   +16 more
core   +1 more source

Identification of functional differences between recombinant human ? and ? cardiac myosin motors [PDF]

, 2012
The myosin isoform composition of the heart is dynamic in health and disease and has been shown to affect contractile velocity and force generation.
Rezavandi, Heresh, Rezavandi, H., Leslie A. Leinwand, Geeves, M., Leinwand, Leslie A., Leinwand, L., Geeves, Michael A., Marieke J. Bloemink, Heresh Rezavandi, Deacon, John C., Bloemink, Marieke J., Deacon, J., John C. Deacon, Bloemink, M., Michael A. Geeves   +14 more
core   +1 more source

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

Advanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa, Arielle Berman, Laura Schwendeman, Ferdows Afghah, Seanbiron Johnson, Ritu Raman   +5 more
wiley   +1 more source

Downregulation of microRNA‐494 drives mitochondrial biogenesis and function in trained muscle

Experimental Physiology
MicroRNAs (miRNAs) are key regulators of cellular processes, including mitochondrial function and energy metabolism. This study explores the regulation of miR‐494 in skeletal muscle and circulation, investigating its response to exercise training and an ...
Natália Pálešová, Klára Gabrišová, Jana Babulicová, Patrik Krumpolec, Zuzana Kovaničová, Tímea Kurdiová, Salvatore Modica, Christian Wolfrum, Jozef Ukropec, Barbara Ukropcová, Miroslav Baláž   +10 more
doaj   +1 more source

UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle? [PDF]

, 2008
Hereditary inclusion body myopathy (HIBM) is a rare neuromuscular disorder caused by mutations in GNE, the key enzyme in the biosynthetic pathway of sialic acid.
North Kathryn N., Mitrani-Rosenbaum, S, Shira Amsili, Stephan Hinderlich, Krause, S, Hinderlich Stephan, Hagit Zer, MacArthur, DG, Mitrani-Rosenbaum Stella, Mitrani-Rosenbaum, Stella, Zer, Hagit, Amsili Shira, Becker-Cohen, M, Hinderlich, S, Amsili, S, Becker-Cohen Michal, Krause, Sabine, Krause Sabine, Kathryn N North, North, Kathryn N., Zer Hagit, Sabine Krause, Daniel G MacArthur, Hinderlich, Stephan, Michal Becker-Cohen, MacArthur Daniel G., Zer, H, MacArthur, Daniel G., Stella Mitrani-Rosenbaum, Becker-Cohen, Michal, Amsili, Shira, North, KN   +31 more
core   +2 more sources

Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

, 2021
Type 2 diabetes mellitus (T2DM) is associated with impaired skeletal muscle function and degeneration of the skeletal muscles. However, the mechanisms underlying the degeneration are not well described in human skeletal muscle. Here we show that skeletal
Jessen, Niels, Just, Jesper, Pers, Tune, Billeskov, Tine, Puri, Pier Lorenzo, Pedersen, Steen B., Pers, Tune H., Rossi, Fabio, Rossi, Fabio M. V., Lin, Lin, Roman, Ines Sanchez, Pedersen, Steen, Bross, Peter, Sánchez-Román Rojas, Inés, Rossi, Fabio M.V., Madaro, Luca, Møller, Andreas Buch, Fred, Rikard Göran, Møller, Andreas Much, Eldrup, Nikolaj, Groppa, Elena, de Paoli, Frank, Stevnsner, Tinna, Jensen, Jonas Brorson, Gormsen, Lars C., Farup, Jean, Cömert, Cagla, Gormsen, Lars, Kampmann, Ulla   +28 more
core   +1 more source