Results 11 to 20 of about 1,066,841 (217)
The human skin microbiome [PDF]
Nature Reviews Microbiology, 2018 Functioning as the exterior interface of the human body with the environment, skin acts as a physical barrier to prevent the invasion of foreign pathogens while providing a home to the commensal microbiota. The harsh physical landscape of skin, particularly the desiccated, nutrient-poor, acidic environment, also contributes to the adversity that ...
Allyson L Byrd +2 more
exaly +3 more sources
PLoS ONE, 2013 The recent era of exploring the human microbiome has provided valuable information on microbial inhabitants, beneficials and pathogens. Screening efforts based on DNA sequencing identified thousands of bacterial lineages associated with human skin but provided only incomplete and crude information on Archaea.
Probst, Alexander J. +2 more
openaire +6 more sources
Photoaging of human skin [PDF]
Photodermatology, Photoimmunology & Photomedicine, 2000 Chronic sun exposure causes photoaging of human skin, a process that is characterized by clinical, histological and biochemical changes which differ from alterations in chronologically aged but sun‐protected skin. Within recent years, substantial progress has been made in unraveling the underlying mechanisms of photoaging.
M, Berneburg +2 more
openaire +2 more sources
Science Translational Medicine, 2013 Clinical and experimental observations in atopic dermatitis and psoriasis reveal new mechanisms of inflammation and antiviral immunity.
openaire +2 more sources
Penetration of Chlorhexidine into Human Skin [PDF]
Antimicrobial Agents and Chemotherapy, 2008 ABSTRACT This study evaluated a model of skin permeation to determine the depth of delivery of chlorhexidine into full-thickness excised human skin following topical application of 2% (wt/vol) aqueous chlorhexidine digluconate. Skin permeation studies were performed on full-thickness human skin using Franz diffusion cells with exposure to ...
Karpanen, Tarja J. +5 more
openaire +4 more sources
Journal of Investigative Dermatology, 1981 An integrated review of the transfer of optical radiation into human skin is presented, aimed at developing useful models for photomedicine. The component chromophores of epidermis and stratum corneum in general determine the attenuation of radiation in these layers, moreso than does optical scattering.
Anderson, R. Rox, Parrish, John A.
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Human Skin Collagenase: Localization and Distribution in Normal Human Skin
Journal of Investigative Dermatology, 1969 ABSTRACTCollagenase activity was measured quantitatively from normal human skin cultured on radioactive, native, reconstituted collagen gels. A regional difference in enzyme activity was demonstrated with skin from the scalp having a specific enzyme activity greater than four-fold that of normal body skin.
openaire +2 more sources
Androgen Metabolism in Human Skin [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1971 ABSTRACT Androgen metabolism has been studied in fetal and adult skin with definitive identification of radiometabolites and the use of a computerized technique for their quantitative determination. After infusion of testosterone-4-14C to previable fetuses, from the 12th to 22nd week of gestation, there was a higher proportion of untransformed ...
CARLO FLAMIGNI +5 more
openaire +3 more sources