Results 141 to 150 of about 24,545 (176)

Mechanisms of human T-lymphotropic virus type 1 transmission and disease

Current Opinion in Virology, 2012
Human T-lymphotrophic virus type-1 (HTLV-1) infects approximately 15-20 million people worldwide, with endemic areas in Japan, the Caribbean, and Africa. The virus is spread through contact with bodily fluids containing infected cells most often from mother to child through breast milk or via blood transfusion.
Michael D, Lairmore, Robyn, Haines, Rajaneesh, Anupam   +2 more
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Detection of antibodies to human T‐lymphotropic virus type 1 (HTLV‐1)

Transfusion, 1988
Sera from 39,898 blood donors were tested for HTLV‐1 antibodies using two enzyme immunoassays (EIA). Sera testing initially reactive (IR) were retested in duplicate by both EIAs. Sera testing repeatedly reactive (RR) were further tested by two Western blots (WB) and by two radioimmunoprecipitation assays (RIPA).
C T, Fang, A E, Williams, S G, Sandler, D J, Slamon, B J, Poiesz   +4 more
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Effects of human T-lymphotropic virus type II on human immunodeficiency virus type 1 phenotypic evolution

Archives of Virology, 2001
Phenotypic change and broader coreceptor usage by HIV-1 have been associated with disease progression. HIV-1 coreceptor usage by primary isolates obtained from HIV-1-infected and HIV-1/HTLV-II-coinfected individuals was determined. HIV-1 was isolated from 15 of 20 HIV-1-infected and 17 of 24 HIV-1/HTLV-II-coinfected individuals.
P C, Guenthner, R C, Hershow, R B, Lal, C S, Dezzutti   +3 more
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Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1

AIDS, 2012
HIV-individuals are at risk for human T-lymphotropic virus (HTLV) coinfection and neurological diseases. Little is known about the impact of HAART among coinfected patients. In this study, 47 out of 428 HIV individuals were coinfected with HTLV (10.9%).
Marcus T T, Silva, Elizabeth S, Neves, Beatriz, Grinsztejn, Otávio, de Melo Espíndola, Doris, Schor, Abelardo, Araújo   +5 more
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Micturitional Disturbance in Human T-Lymphotropic Virus Type-1-Associated Myelopathy

Journal of Spinal Disorders, 1994
We reported the findings of micturitional histories and urodynamic studies in five patients with human T-lymphotropic virus type-1-associated myelopathy. Histories showed that all patients had obstructive as well as irritative micturitional symptoms, and four of their micturitional symptoms appeared from the onset of the disease.
T, Hattori, R, Sakakibara, T, Yamanishi, K, Yasuda, K, Hirayama   +4 more
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Inhibition of Apoptosis by Human T‐Lymphotropic Virus Type‐1 Tax Protein

Annals of the New York Academy of Sciences, 2003
Abstract: Deregulation of the apoptotic process can lead to pathophysiological changes that result in either degenerative diseases or cancer. Although the transactivator Tax has been established as an essential effector of human T‐lymphotropic virus type‐1 (HTLV‐1)‐mediated diseases, which include both a neurodegenerative pathology and leukemia ...
Daniela, Saggioro, Lidia, Acquasaliente, Laura, Daprai, Luigi, Chieco-Bianchi   +3 more
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Prevalence of human T-lymphotropic virus type 1 and 2 infection in Sweden

Scandinavian Journal of Infectious Diseases, 2012
Prevalence data on human T-lymphotropic virus types 1 and 2 (HTLV-1/2) in Sweden have not been updated since 1995. The seroprevalence among blood donors at that time was 0.2/10,000. A few years earlier, a high prevalence of HTLV-2 was found in intravenous drug users (IDUs) in Stockholm (3.4%).
Kerstin, Malm, Bengt, Ekermo, Kristina, Hillgren, Sven, Britton, Hans, Fredlund, Sören, Andersson   +5 more
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Human T-Lymphotropic Virus type 1 infective dermatitis in central Australia

Journal of Clinical Virology, 2013
The Human T-Lymphotropic Virus type 1 (HTLV-1) is a single-stranded RNA retrovirus that preferentially infects CD4+ T cells. The spectrum of diseases that are associated with the most frequent genotype, the HTLV-1 cosmopolitan subtype A, has been well described.
Einsiedel, Lloyd, Cassar, Olivier, Gordon, Lynne, Gessain, Antoine   +3 more
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Drug Targets in Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection

Infectious Disorders - Drug Targets, 2009
Human T-lymphotropic virus type 1 (HTLV-1), the first known human retrovirus, induces various human diseases with a long latency period. The mechanism by which the virus causes diseases is still unknown. Studies indicate that viral replication is important at least for the development of HTLV-1 associated myelopathy, and therefore treatments based on ...
Péter, Boross, Péter, Bagossi, Irene T, Weber, József, Tözsér   +3 more
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Neurological Manifestations of the Human T-lymphotropic Virus Type 1

2017
The human T cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that infects about 20 million individuals worldwide. Its typical neurological presentation is of a chronic, slowly progressive myelopathy named “HTLV-1-associated myelopathy/tropical spastic paraparesis” (HAM/TSP).
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