Results 111 to 120 of about 247,558 (230)

Surface‐Capped Protein Nanoparticles for Nonviral Gene Delivery

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Developing simple, safe, and efficient nonviral delivery systems remains a significant challenge in bioengineering. Nanoparticles offer promising gene delivery capabilities with reduced toxicity; however, long‐standing challenges related to effective plasmid encapsulation and delivery exist.
Fjorela Xhyliu   +9 more
wiley   +1 more source

Human Trafficking: Emergency Department Screening and Referral. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Pulvino C   +7 more
europepmc   +1 more source

Rethinking Extracellular Vesicle Signaling

open access: yesAdvanced Materials, EarlyView.
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley   +1 more source

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

open access: yesAdvanced Materials, EarlyView.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

Patterns of polysubstance use disorder among human trafficking survivors: A latent class analysis. [PDF]

open access: yesAddict Behav
Dell NA   +6 more
europepmc   +1 more source

Anti‐Slip Material‐Based Strategies and Approaches

open access: yesAdvanced Materials Technologies, EarlyView.
This review highlights the principle mechanisms of slipping at the microscale, linking contact mechanics with a friction behavior model for surface interfaces. Main strategies to develop anti‐slip properties to the surfaces are discussed alongside standardized testing approaches.
Sogand Abbaspoor‐Zanjani   +3 more
wiley   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

open access: yesAdvanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon   +6 more
wiley   +1 more source

Abdominal Pain and Vaginal Discharge: An Eye-Opening Simulation Case about Human Trafficking. [PDF]

open access: yesJ Educ Teach Emerg Med
Exeni McAmis NE   +3 more
europepmc   +1 more source

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