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Trafficking in Persons and Human Development: Towards A More Integrated Policy Response [PDF]

open access: yes
Poverty is often regarded as the "root cause" of trafficking, but the linkages between poverty, lack of development and trafficking are complex. For example, there is some evidence to suggest that victims of cross-border trafficking are more likely to ...
Frank Laczko, Gergana Danailova-Trainor
core  

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina   +9 more
wiley   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li   +8 more
wiley   +1 more source

Porous Decellularized Nerve Grafts Facilitate Recellularization and Nerve Regeneration in a Rat Model of Critical Long‐Gap Peripheral Nerve Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Olawale Alimi Alimi   +10 more
wiley   +1 more source

Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology

open access: yesAdvanced Healthcare Materials, EarlyView.
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley   +1 more source

Legal regulation of human trafficking issues in the field of public security

open access: yesХабаршы. Заң сериясы, 2021
It is well known that human trafficking is a very common problem. One of the reasons for this is that the number of victims of this crime worldwide is up to 40.5 million people, criminal activity with a solid income and the presence of a growing trend ...
A. B. Izbassova   +4 more
doaj  

Development of a Vaginal Extracellular Matrix Hydrogel for Combating Genitourinary Syndrome of Menopause

open access: yesAdvanced Materials, EarlyView.
In this study, a vaginal specific ECM hydrogel (vECM) is developed, optimized for intravaginal topical administration, and evaluated for mitigatation of vaginal atrophy associated with menopause. When applied in a rat model of menopause, vECM improves vaginal epithelial thickness and stem cell phenotype, and despite topical application, vECM also ...
Emma I. Zelus   +6 more
wiley   +1 more source

Human trafficking in the hotel industry in the Netherlands: the fine line between service, responsibility and liability

open access: yesResearch in Hospitality Management, 2018
Human trafficking is the fastest growing form of organised crime and the biggest source of income for criminals in Europe. Within the prostitution sector, there is a shift towards less visible forms such as hotel prostitution.
Erwin van der Graaf
doaj   +1 more source

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