Results 181 to 190 of about 238,440 (280)

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

open access: yesAdvanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu   +20 more
wiley   +1 more source

Transit monitoring capacity expansion: Analytics for combating human trafficking

open access: yesTransportation Research Interdisciplinary Perspectives
Human trafficking is a rising complex global problem, and effective anti-trafficking programs can address the problem through four objectives: prevention, prosecution, protection, and partnership, known as the 4Ps.
Kezban Yagci Sokat   +2 more
doaj  

A Review of Prevalence Estimation Methods for Human Trafficking Populations. [PDF]

open access: yesPublic Health Rep, 2022
Schroeder E   +5 more
europepmc   +1 more source

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

open access: yesAdvanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan   +10 more
wiley   +1 more source

A Teach-the-Teacher Module for Human Trafficking Bedside Instruction. [PDF]

open access: yesMedEdPORTAL
Young A   +9 more
europepmc   +1 more source

Assessing healthcare provider knowledge of human trafficking. [PDF]

open access: yesPLoS One, 2022
Exeni McAmis NE   +7 more
europepmc   +1 more source

Intracellular Localization and Trafficking of Fluorescein-Labeled Cisplatin in Human Ovarian Carcinoma Cells [PDF]

open access: bronze, 2005
Roohangiz Safaei   +8 more
openalex   +1 more source

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