Results 211 to 220 of about 238,440 (280)

Tsg101 Control of Human Immunodeficiency Virus Type 1 Gag Trafficking and Release

, 2003
Arthur J. Goff, Lorna S. Ehrlich, Stanley N. Cohen, Charleata A. Carter   +3 more
openalex   +1 more source

Advancements in DNA‐Driven Precision Modulation of Cell Surface Receptor for Programmable Cellular Functions

Advanced Science, EarlyView.
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan, Ming Cai, Yiyu Wang, Hong‐Hui Wang, Zhou Nie   +4 more
wiley   +1 more source

PEARR tool training and implementation: building awareness of violence and human trafficking in a hospital system. [PDF]

Front Med (Lausanne)
Roe-Sepowitz D, Bracy K, Gibbs H, Stafford RL, Bernardin B, Stoklosa H.   +5 more
europepmc   +1 more source

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

Advanced Science, EarlyView.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu, Suhui He, Wen Shi, Jinxia Xu, Shiyang Liu, Zexu Yu, Danyue Li, Qiao Jin, Yumeng Wang, Zian Zhang, Qian Lv, Yuanxiang Ge, Yunjie Li, Xinyue Li, Nan Chen, Xinyu Fu, Yang Yang, Fushan Shi   +17 more
wiley   +1 more source

Factors Influencing Domestic Human Trafficking in Africa: Protocol for a Scoping Review.

JMIR Res Protoc
Belaid L, Sarmiento I, Dion A, Rojas Cardenas A, Cockcroft A, Andersson N.   +5 more
europepmc   +1 more source

The Long Noncoding RNA ΒFaar Promotes White Adipose Tissue Browning and Prevents Diet‐Induced Obesity

Advanced Science, EarlyView.
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang, Bin Huang, Baixue Sha, Danni Gao, Yimeng Qin, Ziyi Li, Xi Chen, Yinuo Jin, Yi Pan, Yanfeng Zhang, Yumeng Shen, Yu Liu, Liang Jin, Fangfang Zhang   +13 more
wiley   +1 more source

Role of PACS-1 in Trafficking of Human Cytomegalovirus Glycoprotein B and Virus Production

, 2003
Colin M. Crump, Chien‐Hui Hung, Laurel Thomas, Lei Wan, Gary Thomas   +4 more
openalex   +1 more source

Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells

Advanced Science, EarlyView.
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas, Salime Bazban‐Shotorbani, Sara Arfan, Karishma Satia, Brian Cunningham, Gauhar Sagindykova, Mymuna Ashna, Aoyu Zhang, Diana Visan, Aisher Chen, Teige Matthews‐Palmer, Mathew Carter, Fiona Blackhall, Kathryn L. Simpson, Caroline Dive, Paul Huang, Sam H. Au   +16 more
wiley   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source