Results 91 to 100 of about 8,063,783 (304)

A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer [PDF]

open access: yes, 2018
Background: Prevention of unnecessary biopsies and overtreatment of indolent disease remains a challenge in the management of prostate cancer. Novel non-invasive tests that can identify clinically significant (intermediate-risk and high-risk) diseases ...
Mills, R.   +104 more
core   +2 more sources

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave   +8 more
wiley   +1 more source

Aberrant dolichol chain lengths as biomarkers for retinitis pigmentosa caused by impaired dolichol biosynthesis

open access: yesJournal of Lipid Research, 2013
We observed a characteristic shortening of plasma and urinary dolichols in retinitis pigmentosa (RP) patients carrying K42E and T206A mutations in the dehydrodolichol diphosphate synthase (DHDDS) gene, using liquid chromatography-mass spectrometry ...
Rong Wen, Byron L. Lam, Ziqiang Guan
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

open access: yesAdvanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake   +5 more
wiley   +1 more source

Presence of N, N′-Substituted p-Phenylenediamine-Derived Quinones in Human Urine

open access: yesToxics
Human exposure to various N,N′-substituted p-phenylenediamine-derived quinones (PPDQs) has been of increasing concern. Recent studies have examined N-phenyl-N′-(1,3-dimethylbutyl)-p-phenylenediamine-derived quinone (6PPDQ) in human urine to evaluate ...
Juxiu Huang   +5 more
doaj   +1 more source

Biotin Derivatives in Human Urine

open access: yesExperimental Biology and Medicine, 1956
SummaryMicrobiological experiments involving direct assays as well as bioautographic procedures indicate that human urine contains relatively large amounts of free bio-tin and very small amounts of a “hydrophilic” biotin derivative that may be “biocytin sulfoxide.” No evidence was found for the existence of other “unusual” biotin derivatives.
L D, WRIGHT, E L, CRESSON, C A, DRISCOLL
openaire   +2 more sources

Monitoring human papillomavirus prevalence in urine samples: a review [Corrigendum]

open access: yes, 2013
Espen Enerly, Cecilia Olofsson, Mari Nygård. Clin Epidemiol. 2013;5:67–79.On page 72, the following sentence was open to misinterpretation: "The most common urine sampling procedure in both female and male populations was first-void urine in ...
Nygård M, Enerly E, Olofsson C
core  

“Smelltronics”—From Gas to Smell Sensing

open access: yesAdvanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono   +7 more
wiley   +1 more source

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

open access: yesAdvanced Materials, EarlyView.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena   +10 more
wiley   +1 more source

Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies. [PDF]

open access: yes, 2013
Detection of the Mycobacterium tuberculosis cell wall antigen lipoarabinomannan (LAM) in urine permits diagnoses of tuberculosis (TB) to be made in HIV-infected patients with advanced immunodeficiency.
Kerkhoff, Andrew D   +23 more
core   +2 more sources

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