Results 171 to 180 of about 146,849 (316)

The Application of Maternal Death Surveillance and Review in Acute Humanitarian Responses. [PDF]

O G Open
Charlton K, Burkhard G, Rijnberg N, Kauffman R, Almohommed A, Daly M, Alhilo HA, Hamid MHA, Abo-Elhassan RAO, Ali KAA, Eltahir EA, Ahmed FAI, Van Braak F, Adingue JG, Casey T, McNally K, Black B.   +16 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Celebrity humanitarian activism in conflicts: a critical descriptive study

, 2012
Includes abstracts.Includes bibliographical references.The phenomenon of celebrities becoming involved in humanitarian activism is by no means new, and yet recently the amount of international attention that it attracts has increased dramatically.
Stoffberg, Kendra
core  

Ethical Challenges Encountered by Humanitarian Aid Workers in Temporary Displacement Camps in the Context of Covid-19. [PDF]

Public Health Ethics
Mellett R, Hunt M.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Redefining state sovereignty: The complexities of Humanitarian intervention and the Responsibility to Protect

, 2009
At the time this statement was made by the former Secretary General of the United Nations, the international community was engulfed in a debate concerning humanitarian intervention and its effect on state sovereignty. Recent interventions in states such
Ofuani, Suzzie Onyeka
core  

An analytical framework for examining the ethical dimensions of innovative humanitarian finance. [PDF]

J Int Humanit Action
Zulkaphil L.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Ethics and methods in disaster health research: a scoping review. [PDF]

J Glob Health
Goniewicz K, Khorram-Manesh A, Naylor K, Carlström E, Wolf A.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source