Results 131 to 140 of about 26,381 (295)

Pushing the boundaries of anticipatory action using machine learning

Data & Policy
Displacement continues to increase at a global scale and is increasingly happening in complex, multicrisis settings, leading to more complex and deeper humanitarian needs.
Alexander Kjærum, Bo S. Madsen
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Determinants of international emergency aid - humanitarian need only ? [PDF]

The authors use an original data set covering more than 400 recent natural disasters to analyze the determinants of international emergency aid. Although humanitarian need is a major determinant of emergency relief payments, the results imply that ...
Redaelli, Silvia, Fink, Guenther
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Mainstreaming HIV/AIDS in Development and Humanitarian Programmes [PDF]

, 2004
AIDS has radically changed the contexts in which development and humanitarian organisations operate, and now they need to adapt their policies and practice accordingly.
Holden, Sue
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The provision of humanitarian aid in complex emergencies: a case study of Somalia

This thesis examines the delivery of humanitarian assistance in Somalia at the turn of the 21st Century. Humanitarian assistance is considered as an ideal and the key question is, can it be effective in a chronic emergency? Humanitarian assistance itself
Rose, Joanne
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Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Humanitarian observatories: insights for reforming humanitarianism from below

Journal of International Humanitarian Action
In the last few decades, there has been a marked turn to “humanitarianism from below” in thinking about and organizing humanitarian action, which is among other expressed in the localization agenda of humanitarian action.
Dorothea Hilhorst, Kaira Zoe Alburo-Cañete, Juan Ricardo Aparicio, Patrick Milabyo Kyamusugulwa, Tadesse Kassa Woldetsadik   +4 more
doaj   +1 more source

Logistics Information and Knowledge Management Issues in Humanitarian Aid Organizations

In this paper, we assess the need for logistics information and knowledge management in humanitarian aid organizations. To do so, we combine literature sources with an extensive case study that we conducted at Médecins sans Frontières–Holland, which ...
Brito, M.P. de, Laan, E.A. van der, Vermaesen, S.C.   +2 more
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Redefining state sovereignty: The complexities of Humanitarian intervention and the Responsibility to Protect

, 2009
At the time this statement was made by the former Secretary General of the United Nations, the international community was engulfed in a debate concerning humanitarian intervention and its effect on state sovereignty. Recent interventions in states such
Ofuani, Suzzie Onyeka
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