Results 181 to 190 of about 219,139 (352)

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Crisis Response in a Changing Climate: Implications of Climate Change for UK Defence Logistics in Humanitarian Assistance and Disaster Relief (HADR) and Military Aid to the Civil Authorities (MACA) Operations [PDF]

open access: hybrid, 2021
Lucia Retter   +26 more
openalex   +1 more source

Australia in the UN Security Council [PDF]

open access: yes
Overview: In this Lowy Institute Analysis, Richard Gowan reviews Australia’s time as a non-permanent member of the Security Council. Gowan argues that while it has not changed the world, Australia has acquitted itself well, bringing extra rigour and ...
Richard Gowan
core  

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Enabling Mobility of War Victims: Amputees in Yemen

open access: yesJournal of Epidemiology and Global Health
Abdullah A. Al-Rabeeah   +3 more
doaj   +1 more source

Early Warning of Food Security Crises in Urban Areas: The Case of Harare, Zimbabwe, 2007 [PDF]

open access: yes
In 2007, the citizens of Harare, Zimbabwe began experiencing an intense food security crisis. The crisis, due to a complex mix of poor government policies, high inflation rates and production decline due to drought, resulted in a massive increase in the ...
Brown, Molly E., Funk, Christopher C.
core   +1 more source

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