Results 181 to 190 of about 14,586 (245)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Protocol for Head StART: A hybrid type II cluster randomized controlled trial evaluating community ART delivery for people newly diagnosed with HIV in refugee settlements in Uganda. [PDF]

PLoS One
Klabbers RE, Mugyenyi A, Nsubuga R, Asaba G, Faustin Z, Kiragga A, Drown L, Mujugira A, Mugambi M, Sharma M, Drain P, Middleton NA, Sveum EM, Lewis S, Muwonge TR, O'Laughlin KN.   +15 more
europepmc   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Trauma and economic displacement: psychological consequences and interventions among Venezuelan refugees in the Americas. [PDF]

Front Psychiatry
Andrade G, Dahawi M.
europepmc   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Voices from the quake zone: a qualitative analysis of Singapore nurses' deployment experience in a WHO-Type-1 fixed emergency medical team. [PDF]

BMC Emerg Med
Shariq Mujtaba F, Cai B, Binte Mohamed Alifi N, Binte Mohd Salleh NR, Ho SF.   +4 more
europepmc   +1 more source

Empowering Ukrainian healthcare and humanitarian aid workers: cocreating a peer support staff wellbeing curriculum. [PDF]

Front Public Health
Welton-Mitchell C, Upadhaya N, Riley A, Torres Kellinghusen J, Hansen A, Skipalska H, Navario P, Castillo TP.   +7 more
europepmc   +1 more source

Self-Help Plus for refugee mothers in Rhino Refugee Settlement, Uganda (SEED): study protocol for a cluster-randomized controlled trial assessing intergenerational effects on preschool-aged children. [PDF]

Trials
Vassiliou PTB, Ainamani HE, Döring S, Gredebäck G, Leku MR, Peltonen K, Scharpf F, Sen U, Sutter M, Walsh JI, Hecker T, Hall J.   +11 more
europepmc   +1 more source

Cancer care interventions for forcibly displaced populations in low- and middle-income countries of the Middle East and North African region affected by humanitarian crises: Protocol for a scoping review. [PDF]

PLoS One
Havlik AL, Ahmed Z, Chadwick PS, Nyhan K, Khoshnood K.   +4 more
europepmc   +1 more source