Results 21 to 30 of about 5,929 (251)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A qualitative study exploring the challenges of humanitarian organisations

, 2011
PurposeThe purpose of this paper is to identify the underlying issues of humanitarian disaster relief logistics in order to provide an understanding of the challenges facing humanitarian organisations in a wider context.Design/methodology/approachThe ...
Christopher Sandwell, Snadwell, Christopher   +1 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Literature review of humanitarian logistics research: trends and challenges

, 2014
Purpose – The purpose of this paper is to present a literature review of humanitarian logistics (HL) that aims to identify trends and suggest some directions for future research.
Tábata Rejane Bertazzo, de Brito, Irineu, Eduardo Queiroz Peres, Bertazzo, Tabata Rejane, Hugo Tsugunobu Yoshida Yoshizaki, Leiras, Adriana, Irineu de Brito Jr, Yoshizaki, Hugo, Adriana Leiras, Brito Junior, Irineu de, Yoshizaki, Hugo Tsugunobu Yoshida, Peres, Eduardo, Peres, Eduardo Queiroz, Bertazzo, Tabata   +13 more
core   +1 more source

Toward a common humanitarian supply chain process model: the Frontline Humanitarian Logistics Initiative

, 2023
Purpose – This study focuses to develop a common humanitarian supply chain process model (HSCPM) that enables effective enterprise resource planning (ERP) systems for NGOs, and the study also investigates the role of modularity as a dynamic capability ...
Diego Vega, Saïah , Félicia, Gyöngyi Kovács, Félicia Saïah, Kovacs, Gyöngyi, Vega, Diego   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A Path to a Public–Private Partnership: Commercial Logistics Concepts Applied to Disaster Response

, 2013
This paper initiates an exploratory investigation with the aim of providing a better understanding of the applicability of several commercial logistics processes to humanitarian logistics.
Swanson, David, David Swanson, R., Smith, Ronn, Smith, Ronn J., R. David Swanson, Ronn J. Smith   +5 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Coordination in humanitarian relief chains: chain coordinators

, 2012
PurposeThe purpose of this paper is to identify chain coordinators and to explore their roles. The paper also highlights certain advantages of coordination, specific competencies of the coordinators, and challenges in the coordination. Design/methodology/
Garnevska, E.V., Marr, N., E.V. Garnevska, Akhtar, P., P. Akhtar, Garnevska, E., Marr, N.E., N.E. Marr   +7 more
core   +1 more source

Models for humanitarian logistics [PDF]

WIT Transactions on Ecology and The Environment, 2012
Emergency logistics is a process to organize and distribute resources during emergency conditions in the area affected by a disastrous event. By means of emergency logistics is possible to reduce disaster impacts that are natural or anthropic, after an event has occurred.
Russo, F., Trecozzi, M. R.
openaire   +2 more sources