Results 91 to 100 of about 4,990 (309)
Humanitarian supply chains: challenging the system
Peer ...
Kovács, Gyöngyi, Heaslip, Graham
openaire +2 more sources
A Robust Optimization Approach to a Real Humanitarian Cold Supply Chain Planning on the COVID-19 crisis [PDF]
, 2022 Behnam Malmir, Christopher W. Zobel
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Transforming Humanitarian Supply Chains Through Green Practices: A Systematic Review
LogisticsBackground: This systematic review explores the integration of green practices into humanitarian supply chains to mitigate environmental impacts and contribute to global decarbonization efforts.
Angie Ramirez-Villamil, Anicia Jaegler
doaj +1 more source
Humanitarian Relief Supply Chain Performance Evaluation: A Literature Review
International Journal of Marketing Studies, 2016 <p>Nowadays small, medium and severe disasters are threatening our world. One of the important role players in alleviating these traits are humanitarian relief supply chains. The increasing number of disasters in our planet earth urges the humanitarian relief supply chains to focus on the assurance of safety of the victims.
TAŞKIN GÜMÜŞ, Alev +1 more
openaire +3 more sources
Potential applications of unmanned ground and aerial vehicles to mitigate challenges of transport and logistics-related critical success factors in the humanitarian supply chain [PDF]
, 2020 Muhammad Azmat, Sebastian Kummer
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source