Results 51 to 60 of about 1,277,685 (364)

Why Do We Need Humanities? [PDF]

open access: yes, 2017
The article is a philosophical reflection of the current status of the humanities in Slovakia. In many areas of our society there is an evident deficit in humanities-science knowledge, reflected also in parliamentary election results in 2016 and having ...
Švihura, Lukáš
core  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Are the humanities threatened by the increasing commercialisation of universities? [PDF]

open access: yes, 2006
As part of the Humanities Festival organised by the Faculty of Humanities & Social Sciences at Dublin City University in May 2006, a debate took place on the question of whether the humanities are threatened by the increasing commercialisation of ...
Sheehan, Helena
core  

Dove gli opposti si attraggono. La matematica tra sapere scientifico e sapere umanistico [PDF]

open access: yesS&F_scienzaefilosofia.it, 2019
Where Opposites Meet: Mathematics Between Science And Humanities The connection between science and mathematics is often considered necessary and insoluble.
ZANZARELLA, IVANO
doaj  

An interdisciplinary perspective on the theology of masculinity

open access: yesVerbum et Ecclesia, 2021
In contemporary academic discourse, there has been a strong tendency to shape theology according to a viewpoint based on the achievements of other sciences, especially those found in philosophy, psychology, sociology and anthropology.
Adam Rybicki, Andrzej K. Jastrzębski
doaj   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Research “Values” in the Humanities: Funding Policies, Evaluation, and Cultural Resources. Some Introductory Remarks

open access: yesHumanities, 2015
In her capacity as guest editor, the author introduces a set of essays examining the trends, risks, needs, pressures, and prospects of the humanities after recent reforms to tertiary education throughout Europe.
Cinzia Ferrini
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

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