Results 51 to 60 of about 1,304,045 (343)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Human-robot co-manipulation of extended objects: Data-driven models and control from analysis of human-human dyads [PDF]
arXiv, 2020 Human teams are able to easily perform collaborative manipulation tasks. However, for a robot and human to simultaneously manipulate an extended object is a difficult task using existing methods from the literature. Our approach in this paper is to use data from human-human dyad experiments to determine motion intent which we use for a physical human ...
arxiv
Are the humanities threatened by the increasing commercialisation of universities? [PDF]
, 2006 As part of the Humanities Festival organised by the Faculty of Humanities & Social Sciences at Dublin City University in May 2006, a debate took place on the question of whether the humanities are threatened by the increasing commercialisation of ...
Sheehan, Helena
core
Ligand recognition by 14‐3‐3 proteins requires negative charges but not necessarily phosphorylation
FEBS Letters, Volume 599, Issue 6, Page 838-847, March 2025.Interactions of 14‐3‐3 proteins with their binding partners are attributed to phosphorylation of the binding partners. In this work, we show that at least one negative charge is required for the peptides to bind 14‐3‐3ε, although phosphorylation is not necessary, and that two negative charges are preferable for high affinity binding.
Seraphine Kamayirese +2 more
wiley +1 more source
Calcium‐sensing receptor‐ and ADAM10‐mediated klotho shedding is regulated by tetraspanin 5
FEBS Letters, Volume 599, Issue 6, Page 866-875, March 2025.The G protein‐coupled calcium‐sensing receptor (CaSR) and the disintegrin/metalloprotease ADAM10 in the renal distal convoluted tubule control systemic levels of Klotho, a cell and tissue homeostasis‐preserving factor. We show that CaSR‐induced cleavage of membrane‐bound αKlotho by ADAM10 requires tetraspanin 5 (Tspan5), a scaffolding and chaperone ...
Zhenan Liu +4 more
wiley +1 more source
Dove gli opposti si attraggono. La matematica tra sapere scientifico e sapere umanistico [PDF]
S&F_scienzaefilosofia.it, 2019 Where Opposites Meet: Mathematics Between Science And Humanities The connection between science and mathematics is often considered necessary and insoluble.
ZANZARELLA, IVANO
doaj
An interdisciplinary perspective on the theology of masculinity
Verbum et Ecclesia, 2021 In contemporary academic discourse, there has been a strong tendency to shape theology according to a viewpoint based on the achievements of other sciences, especially those found in philosophy, psychology, sociology and anthropology.
Adam Rybicki, Andrzej K. Jastrzębski
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Humanities, 2015 In her capacity as guest editor, the author introduces a set of essays examining the trends, risks, needs, pressures, and prospects of the humanities after recent reforms to tertiary education throughout Europe.
Cinzia Ferrini
doaj +1 more source
Human Face as human single identity [PDF]
arXiv, 2014 Human face as a physical human recognition can be used as a unique identity for computer to recognize human by transforming human face with face algorithm as simple text number which can be primary key for human. Human face as single identity for human will be done by making a huge and large world centre human face database, where the human face around
arxiv