Medievalists as Early Adopters of Information Technology
This elliptical history of digital medievalism amply demonstrates that medievalists are often early adopters of new technologies, and also that medievalists have benefitted, time and again, from their interactions with other fields.
John Unsworth
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Canadian Humanities Computing 2004: The Spaces and Places of Technology
None
Maximiliaan Van Woudenberg, ed.
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Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
DETERMINANTS OF COMPLIANCE WITH HEALTH AND SAFETY REGULATIONS IN NIGERIA’S CONSTRUCTION INDUSTRY
The accident rate of the construction industry is disproportionate to the number of its workers compared with other industries. Despite this, the Nigerian construction industry lags behind in tackling the health and safety (H&S) challenges posed by the ...
Nnedinma UMEOKAFOR +2 more
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Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Social Disciplines and humanities in Engineering Training in the Context of the FSES 3++
The article discusses the role of social disciplines and humanities in new educational programmes of engineering training, updated in connection with the introduction of HE FSES 3++.
V. D. Vasilyeva
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The Computer System Enabling Human-Computer Communication
The purpose of this publication is to present the subject of measurement of the brain wave signals and possibilities of communication through such waves. On the basis of the knowledge acquired until present, a system has been created, the purpose of which is to facilitate communication of the people affected with paralysis with the outside world and ...
Sochocka, Anna +2 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

