Results 141 to 150 of about 968,843 (363)

Humanity space. International almanac. Vol. 12, No 1

, 2023
Lazarev Maxim
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Dynamics of sulfate and nitrate in a temperate stream network: combining multi-isotope analysis and generalized linear mixed-effects models for precautionary conservation

Progress in Earth and Planetary Science
Environmental pollution in stream networks is a major concern. In this study, the effects of land-use and geological characteristics on basin-scale sulfate and nitrate dynamics in the Chikusa River basin, Hyogo, Japan, where substantial environmental ...
Lei Fujiyoshi, Ichiro Tayasu, Shiho Yabusaki, Takashi F. Haraguchi, Chikage Yoshimizu, Ken’ichi Ohkushi, Fumiko Furukawa, Masayuki Itoh, Tadashi Yokoyama, Hiromune Mitsuhashi   +9 more
doaj   +1 more source

Personal is political: the alchemy of happiness in Arundhati Roy’s The Ministry of Utmost Happiness

Cogent Arts & Humanities
From the title to the text, happiness matters in The Ministry of Utmost Happiness. However, happiness has garnered less critical attention than the text’s political, cultural, social, gendered, and realist readings, implicating the impossibility of ...
Aisha Jadoon
doaj   +1 more source

Vetoing Humanity: How a few powerful nations hijacked global peace and why reform is needed at the UN Security Council [PDF]

Marc J. Cohen, Amy Croome, E G Nalbandian   +2 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

From Tolerance and Diversity to Inclusion and Celebration; New Horizons for Infusing Queer Theory into Communities [PDF]

, 2017
Tolerance and diversity are at times lauded as the essential terms for modern social justice movements. From school to community settings teachers, public figures, and political leaders throw these terms around to great applaud and acclaim.
McGuire, Laura Jean
core   +1 more source

"Believe in Getter!" or "Believe in humanity!"? Getter Robo Saga as a parable of technology

, 2022
Rafael Galvão de Almeida
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Book review: The politics of humanity: the reality of relief aid [PDF]

, 2013
As UN Under-Secretary-General for Humanitarian Affairs from 2007 until 2010, John Holmes visited some of the most troubled areas of the world and was exposed to the harsh realities of humanitarian aid.
Harmer, Chris
core