Results 121 to 130 of about 968,831 (312)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Postage Due: Stewardship, Stamps and a Watch Pocket [PDF]
, 2014 Why do we forget that people are human? I\u27ve been asking myself that question more and more lately. Partially it\u27s driven by a laundry list of things happening in the world, vitriolic attacks on humanity, both strangers and friends.
Rudy, John M.
core +1 more source
Humans raised by humans raised by humans
, 2018 Humans Raised by Humans Raised by Humans is a collection of poems concerned with inheritance, particularly the things we inherit without knowing that emerge and unravel at unexpected times.
Killmeyer, Sam, author +3 more
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Scientific ReportsAcute ischemic stroke (AIS) remains a major cause of global morbidity and mortality. This study aimed to evaluate the role of albumin corrected anion gap (ACAG) as a prognostic marker for AIS patients. We analyzed data from 1014 AIS patients in the MIMIC-
Yaxin Zhang +5 more
doaj +1 more source
China and the Humanities: At the Crossroads of the Human and the Humane [PDF]
, 2013 This contains the sections of this volume produced by the editor, including the front matter, Preface, Introduction and Index.
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Realizing Art in Multiple Media: How Different Art Forms Capitalize on Varying Elements of Artistic Communication [PDF]
, 2016 Art involves a very large and diverse collection of practices which humanity utilizes to express and communicate. Though these forms are highly similar in many ways, each holds a unique strength in relation to the others. This project was organized in an
Edwards, Jesse, Runnels, Scott
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source