Results 101 to 110 of about 968,831 (312)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Quality of life among individuals with long COVID symptoms in Indonesia at four points of recovery

open access: yesDiscover Mental Health
Purposes We aim to assess the health-related quality of life of individuals with long COVID in Indonesia at  24 months after recovery from the initial COVID-19 diagnosis.
Irma Hidayana   +3 more
doaj   +1 more source

Ambivalence or Melancholia: The Ontogenesis of Religious Sentiment

open access: yesReligions
The psychoanalytic explanation of religious sentiment is genetic, meaning that it probes the psychological processes behind the formation of such sentiment. Freud ascribed the genesis of religious sentiment to human infantile helplessness and ambivalence
Chuansong Huo, Fei Ju
doaj   +1 more source

Kant and Consequentialism (Reflections on Cummiskey’s Kantian Consequentialism) [PDF]

open access: yes, 2018
In his article, the author considers possible forms of relationship between Kant’s ethics and consequentialism. In this context, he analyses David Cummiskey’s views which are expressed in his book, Kantian Consequentialism ...
Gluchman, Vasil
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Human/Humanity, Consciousness and Universe: Informational Relation [PDF]

open access: yes, 2019
From the perspective of the Informational Model of Consciousness elaborated and reported recently on the basis of the last discoveries of the quantum mechanics and astrophysics, the meeting horizon between some ancient coherent empirical
Gaiseanu, Florin
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Effects of Personality on Social Network Disclosure: Do Emotionally Intelligent Individuals Post Inappropriate Content?

open access: yesPsychological Topics, 2012
The prevalence of individuals using social networking sites to stay connected has increased considerably in only a few years and the information posted is now being used by organizations for employee selection.
Kerry Newness   +2 more
doaj  

Humanities for Humanity

open access: yesEngaged Scholar Journal: Community-Engaged Research, Teaching, and Learning, 2018
Since 2007, the Humanities for Humanity (“H4H”) course has brought together student experience beyond the classroom, educational experiences for community members who could not otherwise attend university, discussion of social justice, and studies in the humanities.
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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