Results 121 to 130 of about 95,544 (345)

Family-centered care in pediatric critical care units: A critical review

Journal of Pediatric Critical Care
Family-centered care (FCC) in pediatric intensive care units (PICUs) arises as a response to the need to humanize medical care, integrating families as active allies in the care of the hospitalized child.
Patricia Rubio-Garrido, Leticia Bazo-Hernández, Anna Enrich-Font, Ana María Montserrat-Gala, Cristina Pavón-García, María-Concepción Lasmarías-Ugarte, María-Antonia Martorell-Poveda, María Francisca Jiménez-Herrera   +7 more
doaj   +1 more source

What makes humanity humane.

Journal of biomedical discovery and collaboration, 2006
Scientific and popular lore have promulgated a connection between emotion and the limbic forebrain. However, there are a variety of structures that are considered limbic, and disagreement as to what is meant by "emotion". This essay traces the initial studies upon which the connection between emotion and the limbic forebrain was based and how ...
openaire   +2 more sources

Family Firm Reputation and Humanization: Consumers and the Trust Advantage of Family Firms Under Different Conditions of Brand Familiarity

Family Business Review, 2018
Pioneering conceptual and empirical work ascribe a trust advantage to family firms compared with their nonfamily analogies. But it remains unknown if this trust advantage persists with varying degrees of consumers’ brand familiarity.
Susanne Beck, Reinhard Prügl
semanticscholar   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Humanization in urgent and emergency services: contributions to nursing care.

Revista Gaúcha de Enfermagem, 2019
OBJECTIVE To analyze the evidence of researches carried out on humanization in urgent and emergency care, considering their contributions to nursing care. METHODS Integrative review of LILACS, CINAHL, SciELO, Web of Science, SCOPUS, and BDENF databases,
Kayo Henrique Jardel Feitosa Sousa, C. Damasceno, Camila Aparecida Pinheiro Landim Almeida, Juliana Macêdo Magalhães, M. A. Ferreira   +4 more
semanticscholar   +1 more source

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source

Avaliação dos resultados neonatais do método canguru no Brasil Evaluation of the neonatal outcomes of the kangaroo mother method in Brazil

Jornal de Pediatria, 2008
OBJETIVO: Avaliar os resultados do método canguru no Brasil. MÉTODOS: Estudo de coorte prospectivo comparando 16 unidades que possuíam ou não a segunda fase do método canguru: oito eram centros nacionais de referência para o método canguru (grupo estudo),
Fernando Lamy Filho, Antônio Augusto Moura da Silva, Zeni Carvalho Lamy, Maria Auxiliadora Sousa Mendes Gomes, Maria Elizabeth Lopes Moreira   +4 more
doaj   +1 more source

Humans [PDF]

Current Biology, 2004
Hughes, David A, Cordaux, Richard, Stoneking, Mark   +2 more
openaire   +3 more sources

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

1258 PBMC humanized mouse model with clinical relevance in assessing the safety profile of 4–1BB agonists utomilumab and urelumab [PDF]

, 2022
Destanie Rose, Wenqian He, Bernard S. Buetow, Allison Vitsky, Maggie Lui, Ji-Won Yang, Guoxiang Yang, James L. Keck, Bart Jessen   +8 more
openalex   +1 more source