Results 101 to 110 of about 17,177 (315)

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu   +6 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

Representational structure of health professionals about care delivery to people living with HIV/Aids

open access: yesInvestigación y Educación en Enfermería, 2016
Objective. To analyze the social representation structure of health professionals about care delivery to people living with HIV/AIDS and to reflect on that structure in the light of the National Humanization Policy. Methods.
Camila Rodrigues Barbosa   +2 more
doaj  

Educational spase of free self - determination of a personality in context of pedagogy of freedom [PDF]

open access: yes, 2013
У статті розглянуто основні принципи педагогіки свободи і визначено можливості створення світнього простору вільного самовизначення в педагогічній практиці теперішнього часу.В статье рассмотрены основные принципы педагогики свободы и
Rastrygina, Alla   +1 more
core  

Recovering materiality in institutional work : prizes as an assemblage of human and material entities [PDF]

open access: yes, 2015
In this article we utilize a (posthumanist) practice theory orientation to foreground the neglected role of material elements (e.g., objects and spaces) in institutional work.
Monteiro, Pedro do Nascimento   +1 more
core   +1 more source

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny   +12 more
wiley   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro   +17 more
wiley   +1 more source

Medidas de conforto e comunicação nas ações de cuidado de enfermagem ao paciente crítico

open access: yesRevista Brasileira de Enfermagem
Estudo descritivo, quantitativo, realizado em um hospital universitário de Curitiba-PR. Objetivou-se analisar as ações de cuidado realizadas em um centro de terapia semi-intensiva, na perspectiva da humanização da assistência, e avaliar a presença de ...
Franciele Soares Pott   +3 more
doaj  

Spiritual and Religious Care: Contribution to the Humanization of Assistance

open access: yesRevista Iberoamericana de Bioética, 2018
Our times are characterized by individualism from which arises a constant search for meaning, mostly when a person faces death, caused by disease. Therefore, when we consider the relevance of spirituality to an individual’s well-being it somehow has a ...
Susana Queiroga
doaj   +1 more source

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang   +7 more
wiley   +1 more source

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