Results 71 to 80 of about 17,177 (315)
Reducing stigma and punitive attitudes toward pedophiles through narrative humanization [PDF]
, 2016 Stigmatization and societal punitiveness about pedophilia has a range of potential consequences, such as the social isolation of people with sexual interest in children, and the formation of policies that are not consistent with empirical research ...
Gawronski B. +4 more
core +1 more source
Advanced Science, EarlyView.The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen +15 more
wiley +1 more source
Advanced Science, EarlyView.Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
Humane care in the public hospital setting: nurses’ perspective
Clinical and Biomedical Research, 2014 In 2003, the Brazilian Ministry of Health created a public policy focused on humane care, the National Humanization Policy (NHP). This policy should be implemented in all actions of health promotion, thus changing the traditional model of health ...
Sandra Mara Przybylski +2 more
doaj +2 more sources
Humanidades como disciplina da graduação em Medicina
Revista Brasileira de Educação MédicaApresenta-se o desenvolvimento de uma disciplina em Humanidades Médicas. Objetivou-se examinar contribuições conceituais e práticas do conhecimento humanístico tendo por base o cuidado em saúde.
José Ricardo de Carvalho Mesquita Ayres +4 more
doaj +1 more source
Art of Maternal Womb Painting: term, concept, and technique [PDF]
Revista Brasileira de EnfermagemObjective: to present the term, concept and technique of art of maternal womb painting. Method: a theoretical, exploratory and qualitative study.
Júnia Aparecida Laia da Mata +1 more
doaj +4 more sources
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Compensatory Time vs. Cash Wages: Amending the Fair Labor Standards Act? [PDF]
, 2003 In the 108th Congress, two work hours flexibility bills have been introduced: S. 317 by Senator Gregg and H.R. 1119 by Representative Biggert. Both bills deal with a compensatory time off option (comp time) — though the Gregg proposal is somewhat broader,
Whittaker, William G.
core +1 more source
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. [PDF]
, 2018 Epithelial dysfunction and crypt destruction are defining features of inflammatory bowel disease (IBD). However, current IBD therapies targeting epithelial dysfunction are lacking.
Bayrer, James R +8 more
core +2 more sources
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source