Results 71 to 80 of about 3,337 (305)

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang   +26 more
wiley   +1 more source

The religious dimension of users in the practice of health assistance: perception of health professionals

open access: yesO Mundo da Saúde, 2010
Investigation of a qualitative nature aiming at knowing the opinion of health professionals on the influence of spirituality of users in the process health-disease.
Joseane de Souza Alves   +2 more
doaj  

HEALTHCARE RECEPTION AND HUMANIZED ASSISTANCE IN THE EMERGENCY ROOM FOR ADULTS: NURSES’ PERCEPTIONS

open access: yesRevista de Enfermagem da Universidade Federal de Santa Maria, 2013
http://dx.doi.org/10.5902/217976928279 Aim: to describe the perceptions of nurses that work in the adults emergency room on humanized assistance and healthcare reception and risk classification.
Alcides Viana de Lima Neto   +4 more
doaj   +1 more source

HHI-Assist: A Dataset and Benchmark of Human-Human Interaction in Physical Assistance Scenario

open access: yesIEEE Robotics and Automation Letters
The increasing labor shortage and aging population underline the need for assistive robots to support human care recipients. To enable safe and responsive assistance, robots require accurate human motion prediction in physical interaction scenarios. However, this remains a challenging task due to the variability of assistive settings and the complexity
Saeed Saadatnejad   +4 more
openaire   +2 more sources

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu   +13 more
wiley   +1 more source

Humanization in the process of organ donating for transplantation from the perspective of nurses in intensive care units. [PDF]

open access: yes, 2014
Introdução: O processo de doação de órgãos envolve assistência aos potenciais doadores e aos seus familiares. A humanização nesse contexto requer o envolvimento dos profissionais que participam das diversas atividades desenvolvidas e, dentre eles, os ...
Senna, Lúcia Piva Cabral   +1 more
core   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

open access: yesAdvanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun   +6 more
wiley   +1 more source

Humane care in the public hospital setting: nurses’ perspective

open access: yesClinical and Biomedical Research, 2014
In 2003, the Brazilian Ministry of Health created a public policy focused on humane care, the National Humanization Policy (NHP). This policy should be implemented in all actions of health promotion, thus changing the traditional model of health ...
Sandra Mara Przybylski   +2 more
doaj   +2 more sources

Humanidades como disciplina da graduação em Medicina

open access: yesRevista Brasileira de Educação Médica
Apresenta-se o desenvolvimento de uma disciplina em Humanidades Médicas. Objetivou-se examinar contribuições conceituais e práticas do conhecimento humanístico tendo por base o cuidado em saúde.
José Ricardo de Carvalho Mesquita Ayres   +4 more
doaj   +1 more source

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